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Start Over Author "Patel, Lauren A." Journal nature biotechnology
1 results on '"Patel, Lauren A."'

1. The Wild West of spike-in normalization.

Author

Patel, Lauren A., Cao, Yuwei, Mendenhall, Eric M., Benner, Christopher, and Goren, Alon

Abstract

The proper use of spike-in normalization in ChIP-seq improves sensitivity for detecting genome-wide changes between conditions, but improper use is common, calling some biological conclusions into question. A survey of public datasets generates guidelines for implementation of spike-in normalization for future ChIP-seq experiments. [ABSTRACT FROM AUTHOR]

Published
2024
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