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Start Over Author "Jingnan Pi" Journal nature communications
1 results on '"Jingnan Pi"'

1. microRNA arm-imbalance in part from complementary targets mediated decay promotes gastric cancer progression

Author

Zhengyi Zhang, Jingnan Pi, Dongling Zou, Xiaoshuang Wang, Jiayue Xu, Shan Yu, Ting Zhang, Feng Li, Xianxie Zhang, Hualu Zhao, Fang Wang, Dong Wang, Yanni Ma, and Jia Yu

Subjects
Science
Abstract

Functional miRNAs derived from the 5p or 3p arm of some miRNA duplexes have opposite roles in cancer progression. Here, the authors show that oncogenic miR-574-5p has greater preference in aggressive gastric cancer as compared with miR-574-3p and this arm preference is partly dependent on complementary targets mediated miRNA decay.

Published
2019
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