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Start Over Author "Kaley McCluskey" Journal nature communications
1 results on '"Kaley McCluskey"'

1. DNA replication origins retain mobile licensing proteins

Author

Humberto Sánchez, Kaley McCluskey, Theo van Laar, Edo van Veen, Filip M. Asscher, Belén Solano, John F. X. Diffley, and Nynke H. Dekker

Subjects
Science
Abstract

Eukaryotic DNA replication is regulated to ensure copying of the genome (only) once per cell cycle. Here the authors, using optical trapping and confocal microscopy, demonstrate the dynamics of the origin recognition complex and subsequent intermediates that lead up to the loading of an MCM helicase onto DNA.

Published
2021
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