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Your search keyword '"Ransome van der Hoeven"' showing total 1 results
Start Over Author "Ransome van der Hoeven" Journal nature communications
1 results on '"Ransome van der Hoeven"'

1. Glycolysis regulates KRAS plasma membrane localization and function through defined glycosphingolipids

Author

Junchen Liu, Ransome van der Hoeven, Walaa E. Kattan, Jeffrey T. Chang, Dina Montufar-Solis, Wei Chen, Maurice Wong, Yong Zhou, Carlito B. Lebrilla, and John F. Hancock

Subjects
Science
Abstract

KRAS is a small GTPase that regulates cell proliferation. Here, the authors show that a subset of cell surface glycosphingolipids regulate KRAS plasma membrane localization by modulating inner leaflet lipid composition, uncovering a requirement for KRAS oncogenesis that may have therapeutic potential.

Published
2023
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