Search

Your search keyword '"Utsab R. Shrestha"' showing total 1 results
Start Over Author "Utsab R. Shrestha" Journal nature communications
1 results on '"Utsab R. Shrestha"'

1. Predicting the structural basis of targeted protein degradation by integrating molecular dynamics simulations with structural mass spectrometry

Author

Tom Dixon, Derek MacPherson, Barmak Mostofian, Taras Dauzhenka, Samuel Lotz, Dwight McGee, Sharon Shechter, Utsab R. Shrestha, Rafal Wiewiora, Zachary A. McDargh, Fen Pei, Rajat Pal, João V. Ribeiro, Tanner Wilkerson, Vipin Sachdeva, Ning Gao, Shourya Jain, Samuel Sparks, Yunxing Li, Alexander Vinitsky, Xin Zhang, Asghar M. Razavi, István Kolossváry, Jason Imbriglio, Artem Evdokimov, Louise Bergeron, Wenchang Zhou, Jagat Adhikari, Benjamin Ruprecht, Alex Dickson, Huafeng Xu, Woody Sherman, and Jesus A. Izaguirre

Subjects
Science
Abstract

The formation of ternary degrader-protein complexes is a key step in the targeted degradation of proteins of interest. Here, the authors explore the structure and dynamics of such complexes applying high-performance computer simulations augmented with experimental data.

Published
2022
Full Text
View/download PDF

Catalog

Books, media, physical & digital resources
See catalog results