16 results on '"Yeager, Meredith"'
Search Results
2. Genomic characterization of cervical lymph node metastases in papillary thyroid carcinoma following the Chornobyl accident
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Morton, Lindsay M., Lee, Olivia W., Karyadi, Danielle M., Bogdanova, Tetiana I., Stewart, Chip, Hartley, Stephen W., Breeze, Charles E., Schonfeld, Sara J., Cahoon, Elizabeth K., Drozdovitch, Vladimir, Masiuk, Sergii, Chepurny, Mykola, Zurnadzhy, Liudmyla Yu, Dai, Jieqiong, Krznaric, Marko, Yeager, Meredith, Hutchinson, Amy, Hicks, Belynda D., Dagnall, Casey L., Steinberg, Mia K., Jones, Kristine, Jain, Komal, Jordan, Ben, Machiela, Mitchell J., Dawson, Eric T., Vij, Vibha, Gastier-Foster, Julie M., Bowen, Jay, Mabuchi, Kiyohiko, Hatch, Maureen, Berrington de Gonzalez, Amy, Getz, Gad, Tronko, Mykola D., Thomas, Gerry A., and Chanock, Stephen J.
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- 2024
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3. Mosaic chromosomal alterations in peripheral blood leukocytes of children in sub-Saharan Africa
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Zhou, Weiyin, Fischer, Anja, Ogwang, Martin D., Luo, Wen, Kerchan, Patrick, Reynolds, Steven J., Tenge, Constance N., Were, Pamela A., Kuremu, Robert T., Wekesa, Walter N., Masalu, Nestory, Kawira, Esther, Kinyera, Tobias, Otim, Isaac, Legason, Ismail D., Nabalende, Hadijah, Ayers, Leona W., Bhatia, Kishor, Goedert, James J., Gouveia, Mateus H., Cole, Nathan, Hicks, Belynda, Jones, Kristine, Hummel, Michael, Schlesner, Mathias, Chagaluka, George, Mutalima, Nora, Borgstein, Eric, Liomba, George N., Kamiza, Steve, Mkandawire, Nyengo, Mitambo, Collins, Molyneux, Elizabeth M., Newton, Robert, Glaser, Selina, Kretzmer, Helene, Manning, Michelle, Hutchinson, Amy, Hsing, Ann W., Tettey, Yao, Adjei, Andrew A., Chanock, Stephen J., Siebert, Reiner, Yeager, Meredith, Prokunina-Olsson, Ludmila, Machiela, Mitchell J., and Mbulaiteye, Sam M.
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- 2023
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4. Genome-wide association study of lung adenocarcinoma in East Asia and comparison with a European population
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Shi, Jianxin, Shiraishi, Kouya, Choi, Jiyeon, Matsuo, Keitaro, Chen, Tzu-Yu, Dai, Juncheng, Hung, Rayjean J., Chen, Kexin, Shu, Xiao-Ou, Kim, Young Tae, Landi, Maria Teresa, Lin, Dongxin, Zheng, Wei, Yin, Zhihua, Zhou, Baosen, Song, Bao, Wang, Jiucun, Seow, Wei Jie, Song, Lei, Chang, I-Shou, Hu, Wei, Chien, Li-Hsin, Cai, Qiuyin, Hong, Yun-Chul, Kim, Hee Nam, Wu, Yi-Long, Wong, Maria Pik, Richardson, Brian Douglas, Funderburk, Karen M., Li, Shilan, Zhang, Tongwu, Breeze, Charles, Wang, Zhaoming, Blechter, Batel, Bassig, Bryan A., Kim, Jin Hee, Albanes, Demetrius, Wong, Jason Y. Y., Shin, Min-Ho, Chung, Lap Ping, Yang, Yang, An, She-Juan, Zheng, Hong, Yatabe, Yasushi, Zhang, Xu-Chao, Kim, Young-Chul, Caporaso, Neil E., Chang, Jiang, Ho, James Chung Man, Kubo, Michiaki, Daigo, Yataro, Song, Minsun, Momozawa, Yukihide, Kamatani, Yoichiro, Kobayashi, Masashi, Okubo, Kenichi, Honda, Takayuki, Hosgood, Dean H., Kunitoh, Hideo, Patel, Harsh, Watanabe, Shun-ichi, Miyagi, Yohei, Nakayama, Haruhiko, Matsumoto, Shingo, Horinouchi, Hidehito, Tsuboi, Masahiro, Hamamoto, Ryuji, Goto, Koichi, Ohe, Yuichiro, Takahashi, Atsushi, Goto, Akiteru, Minamiya, Yoshihiro, Hara, Megumi, Nishida, Yuichiro, Takeuchi, Kenji, Wakai, Kenji, Matsuda, Koichi, Murakami, Yoshinori, Shimizu, Kimihiro, Suzuki, Hiroyuki, Saito, Motonobu, Ohtaki, Yoichi, Tanaka, Kazumi, Wu, Tangchun, Wei, Fusheng, Dai, Hongji, Machiela, Mitchell J., Su, Jian, Kim, Yeul Hong, Oh, In-Jae, Lee, Victor Ho Fun, Chang, Gee-Chen, Tsai, Ying-Huang, Chen, Kuan-Yu, Huang, Ming-Shyan, Su, Wu-Chou, Chen, Yuh-Min, Seow, Adeline, Park, Jae Yong, Kweon, Sun-Seog, Chen, Kun-Chieh, Gao, Yu-Tang, Qian, Biyun, Wu, Chen, Lu, Daru, Liu, Jianjun, Schwartz, Ann G., Houlston, Richard, Spitz, Margaret R., Gorlov, Ivan P., Wu, Xifeng, Yang, Ping, Lam, Stephen, Tardon, Adonina, Chen, Chu, Bojesen, Stig E., Johansson, Mattias, Risch, Angela, Bickeböller, Heike, Ji, Bu-Tian, Wichmann, H-Erich, Christiani, David C., Rennert, Gadi, Arnold, Susanne, Brennan, Paul, McKay, James, Field, John K., Shete, Sanjay S., Le Marchand, Loic, Liu, Geoffrey, Andrew, Angeline, Kiemeney, Lambertus A., Zienolddiny-Narui, Shan, Grankvist, Kjell, Johansson, Mikael, Cox, Angela, Taylor, Fiona, Yuan, Jian-Min, Lazarus, Philip, Schabath, Matthew B., Aldrich, Melinda C., Jeon, Hyo-Sung, Jiang, Shih Sheng, Sung, Jae Sook, Chen, Chung-Hsing, Hsiao, Chin-Fu, Jung, Yoo Jin, Guo, Huan, Hu, Zhibin, Burdett, Laurie, Yeager, Meredith, Hutchinson, Amy, Hicks, Belynda, Liu, Jia, Zhu, Bin, Berndt, Sonja I., Wu, Wei, Wang, Junwen, Li, Yuqing, Choi, Jin Eun, Park, Kyong Hwa, Sung, Sook Whan, Liu, Li, Kang, Chang Hyun, Wang, Wen-Chang, Xu, Jun, Guan, Peng, Tan, Wen, Yu, Chong-Jen, Yang, Gong, Sihoe, Alan Dart Loon, Chen, Ying, Choi, Yi Young, Kim, Jun Suk, Yoon, Ho-Il, Park, In Kyu, Xu, Ping, He, Qincheng, Wang, Chih-Liang, Hung, Hsiao-Han, Vermeulen, Roel C. H., Cheng, Iona, Wu, Junjie, Lim, Wei-Yen, Tsai, Fang-Yu, Chan, John K. C., Li, Jihua, Chen, Hongyan, Lin, Hsien-Chih, Jin, Li, Liu, Jie, Sawada, Norie, Yamaji, Taiki, Wyatt, Kathleen, Li, Shengchao A., Ma, Hongxia, Zhu, Meng, Wang, Zhehai, Cheng, Sensen, Li, Xuelian, Ren, Yangwu, Chao, Ann, Iwasaki, Motoki, Zhu, Junjie, Jiang, Gening, Fei, Ke, Wu, Guoping, Chen, Chih-Yi, Chen, Chien-Jen, Yang, Pan-Chyr, Yu, Jinming, Stevens, Victoria L., Fraumeni, Jr, Joseph F., Chatterjee, Nilanjan, Gorlova, Olga Y., Hsiung, Chao Agnes, Amos, Christopher I., Shen, Hongbing, Chanock, Stephen J., Rothman, Nathaniel, Kohno, Takashi, and Lan, Qing
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- 2023
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5. Germline-somatic JAK2 interactions are associated with clonal expansion in myelofibrosis
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Brown, Derek W., Zhou, Weiyin, Wang, Youjin, Jones, Kristine, Luo, Wen, Dagnall, Casey, Teshome, Kedest, Klein, Alyssa, Zhang, Tongwu, Lin, Shu-Hong, Lee, Olivia W., Khan, Sairah, Vo, Jacqueline B., Hutchinson, Amy, Liu, Jia, Wang, Jiahui, Zhu, Bin, Hicks, Belynda, Martin, Andrew St., Spellman, Stephen R., Wang, Tao, Deeg, H. Joachim, Gupta, Vikas, Lee, Stephanie J., Freedman, Neal D., Yeager, Meredith, Chanock, Stephen J., Savage, Sharon A., Saber, Wael, Gadalla, Shahinaz M., and Machiela, Mitchell J.
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- 2022
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6. Two susceptibility loci identified for prostate cancer aggressiveness.
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Berndt, Sonja I, Wang, Zhaoming, Yeager, Meredith, Alavanja, Michael C, Albanes, Demetrius, Amundadottir, Laufey, Andriole, Gerald, Beane Freeman, Laura, Campa, Daniele, Cancel-Tassin, Geraldine, Canzian, Federico, Cornu, Jean-Nicolas, Cussenot, Olivier, Diver, W Ryan, Gapstur, Susan M, Grönberg, Henrik, Haiman, Christopher A, Henderson, Brian, Hutchinson, Amy, Hunter, David J, Key, Timothy J, Kolb, Suzanne, Koutros, Stella, Kraft, Peter, Le Marchand, Loic, Lindström, Sara, Machiela, Mitchell J, Ostrander, Elaine A, Riboli, Elio, Schumacher, Fred, Siddiq, Afshan, Stanford, Janet L, Stevens, Victoria L, Travis, Ruth C, Tsilidis, Konstantinos K, Virtamo, Jarmo, Weinstein, Stephanie, Wilkund, Fredrik, Xu, Jianfeng, Lilly Zheng, S, Yu, Kai, Wheeler, William, Zhang, Han, African Ancestry Prostate Cancer GWAS Consortium, Sampson, Joshua, Black, Amanda, Jacobs, Kevin, Hoover, Robert N, Tucker, Margaret, and Chanock, Stephen J
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African Ancestry Prostate Cancer GWAS Consortium ,Humans ,Prostatic Neoplasms ,Neoplasm Invasiveness ,Genetic Predisposition to Disease ,Case-Control Studies ,Male ,Genetic Loci ,Neoplasm Grading - Abstract
Most men diagnosed with prostate cancer will experience indolent disease; hence, discovering genetic variants that distinguish aggressive from nonaggressive prostate cancer is of critical clinical importance for disease prevention and treatment. In a multistage, case-only genome-wide association study of 12,518 prostate cancer cases, we identify two loci associated with Gleason score, a pathological measure of disease aggressiveness: rs35148638 at 5q14.3 (RASA1, P=6.49 × 10(-9)) and rs78943174 at 3q26.31 (NAALADL2, P=4.18 × 10(-8)). In a stratified case-control analysis, the SNP at 5q14.3 appears specific for aggressive prostate cancer (P=8.85 × 10(-5)) with no association for nonaggressive prostate cancer compared with controls (P=0.57). The proximity of these loci to genes involved in vascular disease suggests potential biological mechanisms worthy of further investigation.
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- 2015
7. A genome-wide association study of marginal zone lymphoma shows association to the HLA region.
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Vijai, Joseph, Wang, Zhaoming, Berndt, Sonja I, Skibola, Christine F, Slager, Susan L, de Sanjose, Silvia, Melbye, Mads, Glimelius, Bengt, Bracci, Paige M, Conde, Lucia, Birmann, Brenda M, Wang, Sophia S, Brooks-Wilson, Angela R, Lan, Qing, de Bakker, Paul IW, Vermeulen, Roel CH, Portlock, Carol, Ansell, Stephen M, Link, Brian K, Riby, Jacques, North, Kari E, Gu, Jian, Hjalgrim, Henrik, Cozen, Wendy, Becker, Nikolaus, Teras, Lauren R, Spinelli, John J, Turner, Jenny, Zhang, Yawei, Purdue, Mark P, Giles, Graham G, Kelly, Rachel S, Zeleniuch-Jacquotte, Anne, Ennas, Maria Grazia, Monnereau, Alain, Bertrand, Kimberly A, Albanes, Demetrius, Lightfoot, Tracy, Yeager, Meredith, Chung, Charles C, Burdett, Laurie, Hutchinson, Amy, Lawrence, Charles, Montalvan, Rebecca, Liang, Liming, Huang, Jinyan, Ma, Baoshan, Villano, Danylo J, Maria, Ann, Corines, Marina, Thomas, Tinu, Novak, Anne J, Dogan, Ahmet, Liebow, Mark, Thompson, Carrie A, Witzig, Thomas E, Habermann, Thomas M, Weiner, George J, Smith, Martyn T, Holly, Elizabeth A, Jackson, Rebecca D, Tinker, Lesley F, Ye, Yuanqing, Adami, Hans-Olov, Smedby, Karin E, De Roos, Anneclaire J, Hartge, Patricia, Morton, Lindsay M, Severson, Richard K, Benavente, Yolanda, Boffetta, Paolo, Brennan, Paul, Foretova, Lenka, Maynadie, Marc, McKay, James, Staines, Anthony, Diver, W Ryan, Vajdic, Claire M, Armstrong, Bruce K, Kricker, Anne, Zheng, Tongzhang, Holford, Theodore R, Severi, Gianluca, Vineis, Paolo, Ferri, Giovanni M, Ricco, Rosalia, Miligi, Lucia, Clavel, Jacqueline, Giovannucci, Edward, Kraft, Peter, Virtamo, Jarmo, Smith, Alex, Kane, Eleanor, Roman, Eve, Chiu, Brian CH, Fraumeni, Joseph F, Wu, Xifeng, Cerhan, James R, Offit, Kenneth, and Chanock, Stephen J
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Humans ,Membrane Glycoproteins ,Computational Biology ,Major Histocompatibility Complex ,Genotype ,Polymorphism ,Single Nucleotide ,European Continental Ancestry Group ,Lymphoma ,B-Cell ,Marginal Zone ,Genome-Wide Association Study ,Butyrophilins ,Polymorphism ,Single Nucleotide ,Lymphoma ,B-Cell ,Marginal Zone - Abstract
Marginal zone lymphoma (MZL) is the third most common subtype of B-cell non-Hodgkin lymphoma. Here we perform a two-stage GWAS of 1,281 MZL cases and 7,127 controls of European ancestry and identify two independent loci near BTNL2 (rs9461741, P=3.95 × 10(-15)) and HLA-B (rs2922994, P=2.43 × 10(-9)) in the HLA region significantly associated with MZL risk. This is the first evidence that genetic variation in the major histocompatibility complex influences MZL susceptibility.
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- 2015
8. The genomic and epigenomic evolutionary history of papillary renal cell carcinomas
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Zhu, Bin, Poeta, Maria Luana, Costantini, Manuela, Zhang, Tongwu, Shi, Jianxin, Sentinelli, Steno, Zhao, Wei, Pompeo, Vincenzo, Cardelli, Maurizio, Alexandrov, Boian S., Otlu, Burcak, Hua, Xing, Jones, Kristine, Brodie, Seth, Dabrowska, Malgorzata Ewa, Toro, Jorge R., Yeager, Meredith, Wang, Mingyi, Hicks, Belynda, Alexandrov, Ludmil B., Brown, Kevin M., Wedge, David C., Chanock, Stephen, Fazio, Vito Michele, Gallucci, Michele, and Landi, Maria Teresa
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- 2020
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9. Mutations in the HPV16 genome induced by APOBEC3 are associated with viral clearance
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Zhu, Bin, Xiao, Yanzi, Yeager, Meredith, Clifford, Gary, Wentzensen, Nicolas, Cullen, Michael, Boland, Joseph F., Bass, Sara, Steinberg, Mia K., Raine-Bennett, Tina, Lee, DongHyuk, Burk, Robert D., Pinheiro, Maisa, Song, Lei, Dean, Michael, Nelson, Chase W., Burdett, Laurie, Yu, Kai, Roberson, David, Lorey, Thomas, Franceschi, Silvia, Castle, Philip E., Walker, Joan, Zuna, Rosemary, Schiffman, Mark, and Mirabello, Lisa
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- 2020
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10. Two high-risk susceptibility loci at 6p25.3 and 14q32.13 for Waldenström macroglobulinemia
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McMaster, Mary L., Berndt, Sonja I., Zhang, Jianqing, Slager, Susan L., Li, Shengchao Alfred, Vajdic, Claire M., Smedby, Karin E., Yan, Huihuang, Birmann, Brenda M., Brown, Elizabeth E., Smith, Alex, Kleinstern, Geffen, Fansler, Mervin M., Mayr, Christine, Zhu, Bin, Chung, Charles C., Park, Ju-Hyun, Burdette, Laurie, Hicks, Belynda D., Hutchinson, Amy, Teras, Lauren R., Adami, Hans-Olov, Bracci, Paige M., McKay, James, Monnereau, Alain, Link, Brian K., Vermeulen, Roel C. H., Ansell, Stephen M., Maria, Ann, Diver, W. Ryan, Melbye, Mads, Ojesina, Akinyemi I., Kraft, Peter, Boffetta, Paolo, Clavel, Jacqueline, Giovannucci, Edward, Besson, Caroline M., Canzian, Federico, Travis, Ruth C., Vineis, Paolo, Weiderpass, Elisabete, Montalvan, Rebecca, Wang, Zhaoming, Yeager, Meredith, Becker, Nikolaus, Benavente, Yolanda, Brennan, Paul, Foretova, Lenka, Maynadie, Marc, Nieters, Alexandra, de Sanjose, Silvia, Staines, Anthony, Conde, Lucia, Riby, Jacques, Glimelius, Bengt, Hjalgrim, Henrik, Pradhan, Nisha, Feldman, Andrew L., Novak, Anne J., Lawrence, Charles, Bassig, Bryan A., Lan, Qing, Zheng, Tongzhang, North, Kari E., Tinker, Lesley F., Cozen, Wendy, Severson, Richard K., Hofmann, Jonathan N., Zhang, Yawei, Jackson, Rebecca D., Morton, Lindsay M., Purdue, Mark P., Chatterjee, Nilanjan, Offit, Kenneth, Cerhan, James R., Chanock, Stephen J., Rothman, Nathaniel, Vijai, Joseph, Goldin, Lynn R., Skibola, Christine F., and Caporaso, Neil E.
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- 2018
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11. Genome-wide association study identifies multiple new loci associated with Ewing sarcoma susceptibility
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Machiela, Mitchell J., Grünewald, Thomas G. P., Surdez, Didier, Reynaud, Stephanie, Mirabeau, Olivier, Karlins, Eric, Rubio, Rebeca Alba, Zaidi, Sakina, Grossetete-Lalami, Sandrine, Ballet, Stelly, Lapouble, Eve, Laurence, Valérie, Michon, Jean, Pierron, Gaelle, Kovar, Heinrich, Gaspar, Nathalie, Kontny, Udo, González-Neira, Anna, Picci, Piero, Alonso, Javier, Patino-Garcia, Ana, Corradini, Nadège, Bérard, Perrine Marec, Freedman, Neal D., Rothman, Nathaniel, Dagnall, Casey L., Burdett, Laurie, Jones, Kristine, Manning, Michelle, Wyatt, Kathleen, Zhou, Weiyin, Yeager, Meredith, Cox, David G., Hoover, Robert N., Khan, Javed, Armstrong, Gregory T., Leisenring, Wendy M., Bhatia, Smita, Robison, Leslie L., Kulozik, Andreas E., Kriebel, Jennifer, Meitinger, Thomas, Metzler, Markus, Hartmann, Wolfgang, Strauch, Konstantin, Kirchner, Thomas, Dirksen, Uta, Morton, Lindsay M., Mirabello, Lisa, Tucker, Margaret A., Tirode, Franck, Chanock, Stephen J., and Delattre, Olivier
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- 2018
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12. Genome-wide association study identifies multiple risk loci for renal cell carcinoma
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Scelo, Ghislaine, primary, Purdue, Mark P., additional, Brown, Kevin M., additional, Johansson, Mattias, additional, Wang, Zhaoming, additional, Eckel-Passow, Jeanette E., additional, Ye, Yuanqing, additional, Hofmann, Jonathan N., additional, Choi, Jiyeon, additional, Foll, Matthieu, additional, Gaborieau, Valerie, additional, Machiela, Mitchell J., additional, Colli, Leandro M., additional, Li, Peng, additional, Sampson, Joshua N., additional, Abedi-Ardekani, Behnoush, additional, Besse, Celine, additional, Blanche, Helene, additional, Boland, Anne, additional, Burdette, Laurie, additional, Chabrier, Amelie, additional, Durand, Geoffroy, additional, Le Calvez-Kelm, Florence, additional, Prokhortchouk, Egor, additional, Robinot, Nivonirina, additional, Skryabin, Konstantin G., additional, Wozniak, Magdalena B., additional, Yeager, Meredith, additional, Basta-Jovanovic, Gordana, additional, Dzamic, Zoran, additional, Foretova, Lenka, additional, Holcatova, Ivana, additional, Janout, Vladimir, additional, Mates, Dana, additional, Mukeriya, Anush, additional, Rascu, Stefan, additional, Zaridze, David, additional, Bencko, Vladimir, additional, Cybulski, Cezary, additional, Fabianova, Eleonora, additional, Jinga, Viorel, additional, Lissowska, Jolanta, additional, Lubinski, Jan, additional, Navratilova, Marie, additional, Rudnai, Peter, additional, Szeszenia-Dabrowska, Neonila, additional, Benhamou, Simone, additional, Cancel-Tassin, Geraldine, additional, Cussenot, Olivier, additional, Baglietto, Laura, additional, Boeing, Heiner, additional, Khaw, Kay-Tee, additional, Weiderpass, Elisabete, additional, Ljungberg, Borje, additional, Sitaram, Raviprakash T., additional, Bruinsma, Fiona, additional, Jordan, Susan J., additional, Severi, Gianluca, additional, Winship, Ingrid, additional, Hveem, Kristian, additional, Vatten, Lars J., additional, Fletcher, Tony, additional, Koppova, Kvetoslava, additional, Larsson, Susanna C., additional, Wolk, Alicja, additional, Banks, Rosamonde E., additional, Selby, Peter J., additional, Easton, Douglas F., additional, Pharoah, Paul, additional, Andreotti, Gabriella, additional, Freeman, Laura E. Beane, additional, Koutros, Stella, additional, Albanes, Demetrius, additional, Männistö, Satu, additional, Weinstein, Stephanie, additional, Clark, Peter E., additional, Edwards, Todd L., additional, Lipworth, Loren, additional, Gapstur, Susan M., additional, Stevens, Victoria L., additional, Carol, Hallie, additional, Freedman, Matthew L., additional, Pomerantz, Mark M., additional, Cho, Eunyoung, additional, Kraft, Peter, additional, Preston, Mark A., additional, Wilson, Kathryn M., additional, Michael Gaziano, J., additional, Sesso, Howard D., additional, Black, Amanda, additional, Freedman, Neal D., additional, Huang, Wen-Yi, additional, Anema, John G., additional, Kahnoski, Richard J., additional, Lane, Brian R., additional, Noyes, Sabrina L., additional, Petillo, David, additional, Teh, Bin Tean, additional, Peters, Ulrike, additional, White, Emily, additional, Anderson, Garnet L., additional, Johnson, Lisa, additional, Luo, Juhua, additional, Buring, Julie, additional, Lee, I-Min, additional, Chow, Wong-Ho, additional, Moore, Lee E., additional, Wood, Christopher, additional, Eisen, Timothy, additional, Henrion, Marc, additional, Larkin, James, additional, Barman, Poulami, additional, Leibovich, Bradley C., additional, Choueiri, Toni K., additional, Mark Lathrop, G., additional, Rothman, Nathaniel, additional, Deleuze, Jean-Francois, additional, McKay, James D., additional, Parker, Alexander S., additional, Wu, Xifeng, additional, Houlston, Richard S., additional, Brennan, Paul, additional, and Chanock, Stephen J., additional
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- 2017
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13. Female chromosome X mosaicism is age-related and preferentially affects the inactivated X chromosome
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Machiela, Mitchell J., primary, Zhou, Weiyin, additional, Karlins, Eric, additional, Sampson, Joshua N., additional, Freedman, Neal D., additional, Yang, Qi, additional, Hicks, Belynda, additional, Dagnall, Casey, additional, Hautman, Christopher, additional, Jacobs, Kevin B., additional, Abnet, Christian C., additional, Aldrich, Melinda C., additional, Amos, Christopher, additional, Amundadottir, Laufey T., additional, Arslan, Alan A., additional, Beane-Freeman, Laura E., additional, Berndt, Sonja I., additional, Black, Amanda, additional, Blot, William J., additional, Bock, Cathryn H., additional, Bracci, Paige M., additional, Brinton, Louise A., additional, Bueno-de-Mesquita, H Bas, additional, Burdett, Laurie, additional, Buring, Julie E., additional, Butler, Mary A., additional, Canzian, Federico, additional, Carreón, Tania, additional, Chaffee, Kari G., additional, Chang, I-Shou, additional, Chatterjee, Nilanjan, additional, Chen, Chu, additional, Chen, Constance, additional, Chen, Kexin, additional, Chung, Charles C., additional, Cook, Linda S., additional, Crous Bou, Marta, additional, Cullen, Michael, additional, Davis, Faith G., additional, De Vivo, Immaculata, additional, Ding, Ti, additional, Doherty, Jennifer, additional, Duell, Eric J., additional, Epstein, Caroline G., additional, Fan, Jin-Hu, additional, Figueroa, Jonine D., additional, Fraumeni, Joseph F., additional, Friedenreich, Christine M., additional, Fuchs, Charles S., additional, Gallinger, Steven, additional, Gao, Yu-Tang, additional, Gapstur, Susan M., additional, Garcia-Closas, Montserrat, additional, Gaudet, Mia M., additional, Gaziano, J. Michael, additional, Giles, Graham G., additional, Gillanders, Elizabeth M., additional, Giovannucci, Edward L., additional, Goldin, Lynn, additional, Goldstein, Alisa M., additional, Haiman, Christopher A., additional, Hallmans, Goran, additional, Hankinson, Susan E., additional, Harris, Curtis C., additional, Henriksson, Roger, additional, Holly, Elizabeth A., additional, Hong, Yun-Chul, additional, Hoover, Robert N., additional, Hsiung, Chao A., additional, Hu, Nan, additional, Hu, Wei, additional, Hunter, David J., additional, Hutchinson, Amy, additional, Jenab, Mazda, additional, Johansen, Christoffer, additional, Khaw, Kay-Tee, additional, Kim, Hee Nam, additional, Kim, Yeul Hong, additional, Kim, Young Tae, additional, Klein, Alison P., additional, Klein, Robert, additional, Koh, Woon-Puay, additional, Kolonel, Laurence N., additional, Kooperberg, Charles, additional, Kraft, Peter, additional, Krogh, Vittorio, additional, Kurtz, Robert C., additional, LaCroix, Andrea, additional, Lan, Qing, additional, Landi, Maria Teresa, additional, Marchand, Loic Le, additional, Li, Donghui, additional, Liang, Xiaolin, additional, Liao, Linda M., additional, Lin, Dongxin, additional, Liu, Jianjun, additional, Lissowska, Jolanta, additional, Lu, Lingeng, additional, Magliocco, Anthony M., additional, Malats, Nuria, additional, Matsuo, Keitaro, additional, McNeill, Lorna H., additional, McWilliams, Robert R., additional, Melin, Beatrice S., additional, Mirabello, Lisa, additional, Moore, Lee, additional, Olson, Sara H., additional, Orlow, Irene, additional, Park, Jae Yong, additional, Patiño-Garcia, Ana, additional, Peplonska, Beata, additional, Peters, Ulrike, additional, Petersen, Gloria M., additional, Pooler, Loreall, additional, Prescott, Jennifer, additional, Prokunina-Olsson, Ludmila, additional, Purdue, Mark P., additional, Qiao, You-Lin, additional, Rajaraman, Preetha, additional, Real, Francisco X., additional, Riboli, Elio, additional, Risch, Harvey A., additional, Rodriguez-Santiago, Benjamin, additional, Ruder, Avima M., additional, Savage, Sharon A., additional, Schumacher, Fredrick, additional, Schwartz, Ann G., additional, Schwartz, Kendra L., additional, Seow, Adeline, additional, Wendy Setiawan, Veronica, additional, Severi, Gianluca, additional, Shen, Hongbing, additional, Sheng, Xin, additional, Shin, Min-Ho, additional, Shu, Xiao-Ou, additional, Silverman, Debra T., additional, Spitz, Margaret R., additional, Stevens, Victoria L., additional, Stolzenberg-Solomon, Rachael, additional, Stram, Daniel, additional, Tang, Ze-Zhong, additional, Taylor, Philip R., additional, Teras, Lauren R., additional, Tobias, Geoffrey S., additional, Van Den Berg, David, additional, Visvanathan, Kala, additional, Wacholder, Sholom, additional, Wang, Jiu-Cun, additional, Wang, Zhaoming, additional, Wentzensen, Nicolas, additional, Wheeler, William, additional, White, Emily, additional, Wiencke, John K., additional, Wolpin, Brian M., additional, Wong, Maria Pik, additional, Wu, Chen, additional, Wu, Tangchun, additional, Wu, Xifeng, additional, Wu, Yi-Long, additional, Wunder, Jay S., additional, Xia, Lucy, additional, Yang, Hannah P., additional, Yang, Pan-Chyr, additional, Yu, Kai, additional, Zanetti, Krista A., additional, Zeleniuch-Jacquotte, Anne, additional, Zheng, Wei, additional, Zhou, Baosen, additional, Ziegler, Regina G., additional, Perez-Jurado, Luis A., additional, Caporaso, Neil E., additional, Rothman, Nathaniel, additional, Tucker, Margaret, additional, Dean, Michael C., additional, Yeager, Meredith, additional, and Chanock, Stephen J., additional
- Published
- 2016
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14. Meta-analysis of genome-wide association studies discovers multiple loci for chronic lymphocytic leukemia
- Author
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Berndt, Sonja I., primary, Camp, Nicola J., additional, Skibola, Christine F., additional, Vijai, Joseph, additional, Wang, Zhaoming, additional, Gu, Jian, additional, Nieters, Alexandra, additional, Kelly, Rachel S., additional, Smedby, Karin E., additional, Monnereau, Alain, additional, Cozen, Wendy, additional, Cox, Angela, additional, Wang, Sophia S., additional, Lan, Qing, additional, Teras, Lauren R., additional, Machado, Moara, additional, Yeager, Meredith, additional, Brooks-Wilson, Angela R., additional, Hartge, Patricia, additional, Purdue, Mark P., additional, Birmann, Brenda M., additional, Vajdic, Claire M., additional, Cocco, Pierluigi, additional, Zhang, Yawei, additional, Giles, Graham G., additional, Zeleniuch-Jacquotte, Anne, additional, Lawrence, Charles, additional, Montalvan, Rebecca, additional, Burdett, Laurie, additional, Hutchinson, Amy, additional, Ye, Yuanqing, additional, Call, Timothy G., additional, Shanafelt, Tait D., additional, Novak, Anne J., additional, Kay, Neil E., additional, Liebow, Mark, additional, Cunningham, Julie M., additional, Allmer, Cristine, additional, Hjalgrim, Henrik, additional, Adami, Hans-Olov, additional, Melbye, Mads, additional, Glimelius, Bengt, additional, Chang, Ellen T., additional, Glenn, Martha, additional, Curtin, Karen, additional, Cannon-Albright, Lisa A., additional, Diver, W Ryan, additional, Link, Brian K., additional, Weiner, George J., additional, Conde, Lucia, additional, Bracci, Paige M., additional, Riby, Jacques, additional, Arnett, Donna K., additional, Zhi, Degui, additional, Leach, Justin M., additional, Holly, Elizabeth A., additional, Jackson, Rebecca D., additional, Tinker, Lesley F., additional, Benavente, Yolanda, additional, Sala, Núria, additional, Casabonne, Delphine, additional, Becker, Nikolaus, additional, Boffetta, Paolo, additional, Brennan, Paul, additional, Foretova, Lenka, additional, Maynadie, Marc, additional, McKay, James, additional, Staines, Anthony, additional, Chaffee, Kari G., additional, Achenbach, Sara J., additional, Vachon, Celine M., additional, Goldin, Lynn R., additional, Strom, Sara S., additional, Leis, Jose F., additional, Weinberg, J. Brice, additional, Caporaso, Neil E., additional, Norman, Aaron D., additional, De Roos, Anneclaire J., additional, Morton, Lindsay M., additional, Severson, Richard K., additional, Riboli, Elio, additional, Vineis, Paolo, additional, Kaaks, Rudolph, additional, Masala, Giovanna, additional, Weiderpass, Elisabete, additional, Chirlaque, María- Dolores, additional, Vermeulen, Roel C. H., additional, Travis, Ruth C., additional, Southey, Melissa C., additional, Milne, Roger L., additional, Albanes, Demetrius, additional, Virtamo, Jarmo, additional, Weinstein, Stephanie, additional, Clavel, Jacqueline, additional, Zheng, Tongzhang, additional, Holford, Theodore R., additional, Villano, Danylo J., additional, Maria, Ann, additional, Spinelli, John J., additional, Gascoyne, Randy D., additional, Connors, Joseph M., additional, Bertrand, Kimberly A., additional, Giovannucci, Edward, additional, Kraft, Peter, additional, Kricker, Anne, additional, Turner, Jenny, additional, Ennas, Maria Grazia, additional, Ferri, Giovanni M., additional, Miligi, Lucia, additional, Liang, Liming, additional, Ma, Baoshan, additional, Huang, Jinyan, additional, Crouch, Simon, additional, Park, Ju-Hyun, additional, Chatterjee, Nilanjan, additional, North, Kari E., additional, Snowden, John A., additional, Wright, Josh, additional, Fraumeni, Joseph F., additional, Offit, Kenneth, additional, Wu, Xifeng, additional, de Sanjose, Silvia, additional, Cerhan, James R., additional, Chanock, Stephen J., additional, Rothman, Nathaniel, additional, and Slager, Susan L., additional
- Published
- 2016
- Full Text
- View/download PDF
15. Evolution of multiple cell clones over a 29-year period of a CLL patient.
- Author
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Zhao, Zhikun, Goldin, Lynn, Liu, Shiping, Wu, Liang, Zhou, Weiyin, Lou, Hong, Yu, Qichao, Tsang, Shirley X., Jiang, Miaomiao, Li, Fuqiang, McMaster, MaryLou, Li, Yang, Lin, Xinxin, Wang, Zhifeng, Xu, Liqin, Marti, Gerald, Li, Guibo, Wu, Kui, Yeager, Meredith, and Yang, Huanming
- Published
- 2016
- Full Text
- View/download PDF
16. Atlas of prostate cancer heritability in European and African-American men pinpoints tissue-specific regulation.
- Author
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Gusev A, Shi H, Kichaev G, Pomerantz M, Li F, Long HW, Ingles SA, Kittles RA, Strom SS, Rybicki BA, Nemesure B, Isaacs WB, Zheng W, Pettaway CA, Yeboah ED, Tettey Y, Biritwum RB, Adjei AA, Tay E, Truelove A, Niwa S, Chokkalingam AP, John EM, Murphy AB, Signorello LB, Carpten J, Leske MC, Wu SY, Hennis AJ, Neslund-Dudas C, Hsing AW, Chu L, Goodman PJ, Klein EA, Witte JS, Casey G, Kaggwa S, Cook MB, Stram DO, Blot WJ, Eeles RA, Easton D, Kote-Jarai Z, Al Olama AA, Benlloch S, Muir K, Giles GG, Southey MC, Fitzgerald LM, Gronberg H, Wiklund F, Aly M, Henderson BE, Schleutker J, Wahlfors T, Tammela TL, Nordestgaard BG, Key TJ, Travis RC, Neal DE, Donovan JL, Hamdy FC, Pharoah P, Pashayan N, Khaw KT, Stanford JL, Thibodeau SN, McDonnell SK, Schaid DJ, Maier C, Vogel W, Luedeke M, Herkommer K, Kibel AS, Cybulski C, Wokolorczyk D, Kluzniak W, Cannon-Albright L, Teerlink C, Brenner H, Dieffenbach AK, Arndt V, Park JY, Sellers TA, Lin HY, Slavov C, Kaneva R, Mitev V, Batra J, Spurdle A, Clements JA, Teixeira MR, Pandha H, Michael A, Paulo P, Maia S, Kierzek A, Conti DV, Albanes D, Berg C, Berndt SI, Campa D, Crawford ED, Diver WR, Gapstur SM, Gaziano JM, Giovannucci E, Hoover R, Hunter DJ, Johansson M, Kraft P, Le Marchand L, Lindström S, Navarro C, Overvad K, Riboli E, Siddiq A, Stevens VL, Trichopoulos D, Vineis P, Yeager M, Trynka G, Raychaudhuri S, Schumacher FR, Price AL, Freedman ML, Haiman CA, and Pasaniuc B
- Subjects
- Acetylation, Atlases as Topic, Cell Line, Tumor, Genetic Loci, Genome-Wide Association Study, Histones genetics, Histones metabolism, Humans, Linkage Disequilibrium, Male, Polymorphism, Single Nucleotide, Prostatic Neoplasms ethnology, Prostatic Neoplasms pathology, Black or African American, Epigenesis, Genetic, Genetic Predisposition to Disease, Inheritance Patterns, Prostatic Neoplasms genetics, White People
- Abstract
Although genome-wide association studies have identified over 100 risk loci that explain ∼33% of familial risk for prostate cancer (PrCa), their functional effects on risk remain largely unknown. Here we use genotype data from 59,089 men of European and African American ancestries combined with cell-type-specific epigenetic data to build a genomic atlas of single-nucleotide polymorphism (SNP) heritability in PrCa. We find significant differences in heritability between variants in prostate-relevant epigenetic marks defined in normal versus tumour tissue as well as between tissue and cell lines. The majority of SNP heritability lies in regions marked by H3k27 acetylation in prostate adenoc7arcinoma cell line (LNCaP) or by DNaseI hypersensitive sites in cancer cell lines. We find a high degree of similarity between European and African American ancestries suggesting a similar genetic architecture from common variation underlying PrCa risk. Our findings showcase the power of integrating functional annotation with genetic data to understand the genetic basis of PrCa.
- Published
- 2016
- Full Text
- View/download PDF
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