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Start Over Author "Benabid, Adam" Journal nature genetics
2 results on '"Benabid, Adam"'

2. Inflammation drives pressure on TP53mutant clones in myeloproliferative neoplasms

Author

Benabid, Adam and Schneider, Rebekka K.

Abstract

Transformation of a myeloproliferative neoplasm to a secondary acute myeloid leukemia is rare but devastating. Single-cell, multi-omic characterization of hematopoietic stem and progenitor cells now shows the role of inflammation in transformation driven by mutations in TP53, with effects on the mutant clone but also non-mutant counterparts.

Published
2023
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