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Your search keyword '"Inoue, Kimiko"' showing total 9 results
Start Over Author "Inoue, Kimiko" Journal nature genetics
9 results on '"Inoue, Kimiko"'

2. Differentiated cells are more efficient than adult stem cells for cloning by somatic cell nuclear transfer

Author

Sung, Li-Ying, primary, Gao, Shaorong, additional, Shen, Hongmei, additional, Yu, Hui, additional, Song, Yifang, additional, Smith, Sadie L, additional, Chang, Ching-Chien, additional, Inoue, Kimiko, additional, Kuo, Lynn, additional, Lian, Jin, additional, Li, Ao, additional, Tian, X Cindy, additional, Tuck, David P, additional, Weissman, Sherman M, additional, Yang, Xiangzhong, additional, and Cheng, Tao, additional

Published
2006
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3. Deletion of Peg10, an imprinted gene acquired from a retrotransposon, causes early embryonic lethality

Author

Ono, Ryuichi, primary, Nakamura, Kenji, additional, Inoue, Kimiko, additional, Naruse, Mie, additional, Usami, Takako, additional, Wakisaka-Saito, Noriko, additional, Hino, Toshiaki, additional, Suzuki-Migishima, Rika, additional, Ogonuki, Narumi, additional, Miki, Hiromi, additional, Kohda, Takashi, additional, Ogura, Atsuo, additional, Yokoyama, Minesuke, additional, Kaneko-Ishino, Tomoko, additional, and Ishino, Fumitoshi, additional

Published
2005
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4. Oligo-astheno-teratozoospermia in mice lacking Cnot7, a regulator of retinoid X receptor beta

Author

Nakamura, Takahisa, primary, Yao, Ryoji, additional, Ogawa, Takehiko, additional, Suzuki, Toru, additional, Ito, Chizuru, additional, Tsunekawa, Naoki, additional, Inoue, Kimiko, additional, Ajima, Rieko, additional, Miyasaka, Takashi, additional, Yoshida, Yutaka, additional, Ogura, Atsuo, additional, Toshimori, Kiyotaka, additional, Noce, Toshiaki, additional, Yamamoto, Tadashi, additional, and Noda, Tetsuo, additional

Published
2004
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5. Early death of mice cloned from somatic cells

Author

Ogonuki, Narumi, primary, Inoue, Kimiko, additional, Yamamoto, Yoshie, additional, Noguchi, Yoko, additional, Tanemura, Kentaro, additional, Suzuki, Osamu, additional, Nakayama, Hiroyuki, additional, Doi, Kunio, additional, Ohtomo, Yukiko, additional, Satoh, Michiko, additional, Nishida, Akira, additional, and Ogura, Atsuo, additional

Published
2002
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7. Differentiated cells are more efficient than adult stem cells for cloning by somatic cell nuclear transfer.

Author

Li-Ying Sung, Shaorong Gao, Hongmei Shen, Hui Yu, Yifang Song, Smith, Sadie L., Ching-Chien Chang, Inoue, Kimiko, Lynn Kuo, Jin Lian, Ao Li, Tian, X. Cindy, Tuck, David P., Weissman, Sherman M., Xiangzhong Yang, and Tao Cheng

Subjects
TRANSPLANTATION of cell nuclei, GENETIC engineering, SOMATIC cells, STEM cells, CLONING, HUMAN genetics
Abstract

Since the creation of Dolly via somatic cell nuclear transfer (SCNT), more than a dozen species of mammals have been cloned using this technology. One hypothesis for the limited success of cloning via SCNT (1%–5%) is that the clones are likely to be derived from adult stem cells. Support for this hypothesis comes from the findings that the reproductive cloning efficiency for embryonic stem cells is five to ten times higher than that for somatic cells as donors and that cloned pups cannot be produced directly from cloned embryos derived from differentiated B and T cells or neuronal cells. The question remains as to whether SCNT-derived animal clones can be derived from truly differentiated somatic cells. We tested this hypothesis with mouse hematopoietic cells at different differentiation stages: hematopoietic stem cells, progenitor cells and granulocytes. We found that cloning efficiency increases over the differentiation hierarchy, and terminally differentiated postmitotic granulocytes yield cloned pups with the greatest cloning efficiency. [ABSTRACT FROM AUTHOR]

Published
2006
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8. Reply to “On the cloning of animals from terminally differentiated cells”.

Author

Xiangzhong Yang, Tao Cheng, Li-Ying Sung, Shaorong Gao, Hongmei Shen, Hui Yu, Yifang Song, Smith, Sadie L., Tuck, David P., Inoue, Kimiko, and Weissman, Sherman M.

Subjects
LETTERS to the editor, CLONING
Abstract

A response by Yang to a letter to the editor about their article "Differentiated cells are more efficient than adult stem cells for cloning by somatic cell nuclear transfer," is presented.

Published
2007
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9. Deletion of Peg10, an imprinted gene acquired from a retrotransposon, causes early embryonic lethality.

Author

Ono R, Nakamura K, Inoue K, Naruse M, Usami T, Wakisaka-Saito N, Hino T, Suzuki-Migishima R, Ogonuki N, Miki H, Kohda T, Ogura A, Yokoyama M, Kaneko-Ishino T, and Ishino F

Subjects
Animals, Apoptosis Regulatory Proteins, DNA Methylation, DNA-Binding Proteins, Female, Fetal Growth Retardation genetics, Gene Deletion, Gene Expression Regulation, Developmental, Mice, Mice, Knockout, Nuclear Proteins metabolism, Parthenogenesis genetics, Placenta physiology, Pregnancy, RNA-Binding Proteins, Transcription Factors metabolism, Embryo Loss genetics, Genomic Imprinting, Nuclear Proteins genetics, Placenta pathology, Retroelements, Transcription Factors genetics
Abstract

By comparing mammalian genomes, we and others have identified actively transcribed Ty3/gypsy retrotransposon-derived genes with highly conserved DNA sequences and insertion sites. To elucidate the functions of evolutionarily conserved retrotransposon-derived genes in mammalian development, we produced mice that lack one of these genes, Peg10 (paternally expressed 10), which is a paternally expressed imprinted gene on mouse proximal chromosome 6. The Peg10 knockout mice showed early embryonic lethality owing to defects in the placenta. This indicates that Peg10 is critical for mouse parthenogenetic development and provides the first direct evidence of an essential role of an evolutionarily conserved retrotransposon-derived gene in mammalian development.

Published
2006
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