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Your search keyword '"Yin, Xian"' showing total 8 results
Start Over Author "Yin, Xian" Journal nature genetics
8 results on '"Yin, Xian"'

1. Exome sequencing identifies MVK mutations in disseminated superficial actinic porokeratosis

Author

Zhang, Sheng-Quan, primary, Jiang, Tao, additional, Li, Min, additional, Zhang, Xin, additional, Ren, Yun-Qing, additional, Wei, Sheng-Cai, additional, Sun, Liang-Dan, additional, Cheng, Hui, additional, Li, Yang, additional, Yin, Xian-Yong, additional, Hu, Zheng-Mao, additional, Wang, Zhen-Ying, additional, Liu, Yuan, additional, Guo, Bi-Rong, additional, Tang, Hua-Yang, additional, Tang, Xian-Fa, additional, Ding, Yan-Tao, additional, Wang, Jian-Bo, additional, Li, Ping, additional, Wu, Bao-Yu, additional, Wang, Wen, additional, Yuan, Xiang-Feng, additional, Hou, Jun-Sheng, additional, Ha, Wei-Wei, additional, Wang, Wen-Ju, additional, Zhai, Yu-Juan, additional, Wang, Jing, additional, Qian, Fang-Fang, additional, Zhou, Fu-Sheng, additional, Chen, Gang, additional, Zuo, Xian-Bo, additional, Zheng, Xiao-Dong, additional, Sheng, Yu-Jun, additional, Gao, Jin-Ping, additional, Liang, Bo, additional, Li, Pan, additional, Zhu, Jun, additional, Xiao, Feng-Li, additional, Wang, Pei-Guang, additional, Cui, Yong, additional, Li, Hui, additional, Liu, Sheng-Xiu, additional, Gao, Min, additional, Fan, Xing, additional, Shen, Song-Ke, additional, Zeng, Ming, additional, Sun, Guang-Qing, additional, Xu, Yu, additional, Hu, Jing-Chu, additional, He, Ting-Ting, additional, Li, Ying-Rui, additional, Yang, Huan-Ming, additional, Wang, Jian, additional, Yu, Zhong-Yi, additional, Zhang, Hui-Feng, additional, Hu, Xin, additional, Yang, Ke, additional, Wang, Jie, additional, Zhao, Shi-Xiang, additional, Zhou, You-Wen, additional, Liu, Jian-Jun, additional, Du, Wei-Dong, additional, Zhang, Li, additional, Xia, Kun, additional, Yang, Sen, additional, Wang, Jun, additional, and Zhang, Xue-Jun, additional

Published
2012
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2. A genome-wide association study in Han Chinese identifies multiple susceptibility loci for IgA nephropathy

Author

Yu, Xue-Qing, primary, Li, Ming, additional, Zhang, Hong, additional, Low, Hui-Qi, additional, Wei, Xin, additional, Wang, Jin-Quan, additional, Sun, Liang-Dan, additional, Sim, Kar-Seng, additional, Li, Yi, additional, Foo, Jia-Nee, additional, Wang, Wei, additional, Li, Zhi-Jian, additional, Yin, Xian-Yong, additional, Tang, Xue-Qing, additional, Fan, Li, additional, Chen, Jian, additional, Li, Rong-Shan, additional, Wan, Jian-Xin, additional, Liu, Zhang-Suo, additional, Lou, Tan-Qi, additional, Zhu, Li, additional, Huang, Xiao-Jun, additional, Zhang, Xue-Jun, additional, Liu, Zhi-Hong, additional, and Liu, Jian-Jun, additional

Published
2011
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3. Genome-wide association study identifies a susceptibility locus for schizophrenia in Han Chinese at 11p11.2

Author

Yue, Wei-Hua, primary, Wang, Hai-Feng, additional, Sun, Liang-Dan, additional, Tang, Fu-Lei, additional, Liu, Zhong-Hua, additional, Zhang, Hong-Xing, additional, Li, Wen-Qiang, additional, Zhang, Yan-Ling, additional, Zhang, Yang, additional, Ma, Cui-Cui, additional, Du, Bo, additional, Wang, Li-Fang, additional, Ren, Yun-Qing, additional, Yang, Yong-Feng, additional, Hu, Xiao-Feng, additional, Wang, Yi, additional, Deng, Wei, additional, Tan, Li-Wen, additional, Tan, Yun-Long, additional, Chen, Qi, additional, Xu, Guang-Ming, additional, Yang, Gui-Gang, additional, Zuo, Xian-bo, additional, Yan, Hao, additional, Ruan, Yan-Yan, additional, Lu, Tian-Lan, additional, Han, Xue, additional, Ma, Xiao-Hong, additional, Wang, Yan, additional, Cai, Li-Wei, additional, Jin, Chao, additional, Zhang, Hong-Yan, additional, Yan, Jun, additional, Mi, Wei-Feng, additional, Yin, Xian-Yong, additional, Ma, Wen-Bin, additional, Liu, Qi, additional, Kang, Lan, additional, Sun, Wei, additional, Pan, Cheng-Ying, additional, Shuang, Mei, additional, Yang, Fu-De, additional, Wang, Chuan-Yue, additional, Yang, Jian-Li, additional, Li, Ke-Qing, additional, Ma, Xin, additional, Li, Ling-Jiang, additional, Yu, Xin, additional, Li, Qi-Zhai, additional, Huang, Xun, additional, Lv, Lu-Xian, additional, Li, Tao, additional, Zhao, Guo-Ping, additional, Huang, Wei, additional, Zhang, Xue-Jun, additional, and Zhang, Dai, additional

Published
2011
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4. Genome-wide association study identifies two new susceptibility loci for atopic dermatitis in the Chinese Han population

Author

Sun, Liang-Dan, primary, Xiao, Feng-Li, additional, Li, Yang, additional, Zhou, Wen-Ming, additional, Tang, Hua-Yang, additional, Tang, Xian-Fa, additional, Zhang, Hui, additional, Schaarschmidt, Heidi, additional, Zuo, Xian-Bo, additional, Foelster-Holst, Regina, additional, He, Su-Min, additional, Shi, Mei, additional, Liu, Qiang, additional, Lv, Yong-Mei, additional, Chen, Xi-Lan, additional, Zhu, Kun-Ju, additional, Guo, Yi-Feng, additional, Hu, Da-Yan, additional, Li, Ming, additional, Li, Min, additional, Zhang, Yan-Hong, additional, Zhang, Xin, additional, Tang, Jian-Ping, additional, Guo, Bi-Rong, additional, Wang, Hua, additional, Liu, Yuan, additional, Zou, Xiao-Yan, additional, Zhou, Fu-Sheng, additional, Liu, Xiao-Yan, additional, Chen, Gang, additional, Ma, Lin, additional, Zhang, Shu-Mei, additional, Jiang, Ai-Ping, additional, Zheng, Xiao-Dong, additional, Gao, Xing-Hua, additional, Li, Pan, additional, Tu, Cai-Xia, additional, Yin, Xian-Yong, additional, Han, Xiu-Ping, additional, Ren, Yun-Qing, additional, Song, Shun-Peng, additional, Lu, Zhi-Yong, additional, Zhang, Xing-Lian, additional, Cui, Yong, additional, Chang, Jing, additional, Gao, Min, additional, Luo, Xiao-Yan, additional, Wang, Pei-Guang, additional, Dai, Xing, additional, Su, Wei, additional, Li, Hui, additional, Shen, Chun-Pin, additional, Liu, Sheng-Xiu, additional, Feng, Xiao-Bo, additional, Yang, Chun-Jun, additional, Lin, Guo-Shu, additional, Wang, Zai-Xing, additional, Huang, Jian-Qing, additional, Fan, Xing, additional, Wang, Yan, additional, Bao, Yi-Xiao, additional, Yang, Sen, additional, Liu, Jian-Jun, additional, Franke, Andre, additional, Weidinger, Stephan, additional, Yao, Zhi-Rong, additional, and Zhang, Xue-Jun, additional

Published
2011
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5. Genome-wide association study for vitiligo identifies susceptibility loci at 6q27 and the MHC

Author

Quan, Cheng, primary, Ren, Yun-Qing, additional, Xiang, Lei-Hong, additional, Sun, Liang-Dan, additional, Xu, Ai-E, additional, Gao, Xing-Hua, additional, Chen, Hong-Duo, additional, Pu, Xiong-Ming, additional, Wu, Ri-Na, additional, Liang, Chao-Zhao, additional, Li, Jia-Bin, additional, Gao, Tian-Wen, additional, Zhang, Jian-Zhong, additional, Wang, Xiu-Li, additional, Wang, Jun, additional, Yang, Rong-Ya, additional, Liang, Ling, additional, Yu, Jian-Bin, additional, Zuo, Xian-Bo, additional, Zhang, Sheng-Quan, additional, Zhang, Shu-Mei, additional, Chen, Gang, additional, Zheng, Xiao-Dong, additional, Li, Pan, additional, Zhu, Jun, additional, Li, Yong-Wei, additional, Wei, Xiao-Dong, additional, Hong, Wei-Song, additional, Ye, Ying, additional, Zhang, Yong, additional, Wu, Wei-Su, additional, Cheng, Hui, additional, Dong, Pu-Ling, additional, Hu, Da-Yan, additional, Li, Yang, additional, Li, Min, additional, Zhang, Xin, additional, Tang, Hua-Yang, additional, Tang, Xian-Fa, additional, Xu, Sheng-Xin, additional, He, Su-Min, additional, Lv, Yong-Mei, additional, Shen, Min, additional, Jiang, Hong-Quan, additional, Wang, Ying, additional, Li, Kai, additional, Kang, Xiao-Jing, additional, Liu, Yu-Qin, additional, Sun, Li, additional, Liu, Zhi-Fang, additional, Xie, Shao-Qiong, additional, Zhu, Cheng-Yao, additional, Xu, Qiang, additional, Gao, Jin-Ping, additional, Hu, Wen-Long, additional, Ni, Cheng, additional, Pan, Ting-Meng, additional, Li, Yun, additional, Yao, Sha, additional, He, Cai-Feng, additional, Liu, Yang-Sheng, additional, Yu, Ze-Ying, additional, Yin, Xian-Yong, additional, Zhang, Feng-Yu, additional, Yang, Sen, additional, Zhou, Youwen, additional, and Zhang, Xue-Jun, additional

Published
2010
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6. Psoriasis genome-wide association study identifies susceptibility variants within LCE gene cluster at 1q21

Author

Zhang, Xue-Jun, primary, Huang, Wei, additional, Yang, Sen, additional, Sun, Liang-Dan, additional, Zhang, Feng-Yu, additional, Zhu, Qi-Xing, additional, Zhang, Fu-Ren, additional, Zhang, Chi, additional, Du, Wen-Hui, additional, Pu, Xiong-Ming, additional, Li, Hui, additional, Xiao, Feng-Li, additional, Wang, Zai-Xing, additional, Cui, Yong, additional, Hao, Fei, additional, Zheng, Jie, additional, Yang, Xue-Qin, additional, Cheng, Hui, additional, He, Chun-Di, additional, Liu, Xiao-Ming, additional, Xu, Li-Min, additional, Zheng, Hou-Feng, additional, Zhang, Shu-Mei, additional, Zhang, Jian-Zhong, additional, Wang, Hong-Yan, additional, Cheng, Yi-Lin, additional, Ji, Bi-Hua, additional, Fang, Qiao-Yun, additional, Li, Yu-Zhen, additional, Zhou, Fu-Sheng, additional, Han, Jian-Wen, additional, Quan, Cheng, additional, Chen, Bin, additional, Liu, Jun-Lin, additional, Lin, Da, additional, Fan, Li, additional, Zhang, An-Ping, additional, Liu, Sheng-Xiu, additional, Yang, Chun-Jun, additional, Wang, Pei-Guang, additional, Zhou, Wen-Ming, additional, Lin, Guo-Shu, additional, Wu, Wei-Dong, additional, Fan, Xing, additional, Gao, Min, additional, Yang, Bao-Qi, additional, Lu, Wen-Sheng, additional, Zhang, Zheng, additional, Zhu, Kun-Ju, additional, Shen, Song-Ke, additional, Li, Min, additional, Zhang, Xiao-Yan, additional, Cao, Ting-Ting, additional, Ren, Wei, additional, Zhang, Xin, additional, He, Jun, additional, Tang, Xian-Fa, additional, Lu, Shun, additional, Yang, Jian-Qiang, additional, Zhang, Lin, additional, Wang, Dan-Ni, additional, Yuan, Feng, additional, Yin, Xian-Yong, additional, Huang, Hong-Jie, additional, Wang, Hai-Feng, additional, Lin, Xin-Yi, additional, and Liu, Jian-Jun, additional

Published
2009
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7. A genome-wide association study in Han Chinese identifies multiple susceptibility loci for IgA nephropathy.

Author

Yu, Xue-Qing, Li, Ming, Zhang, Hong, Low, Hui-Qi, Wei, Xin, Wang, Jin-Quan, Sun, Liang-Dan, Sim, Kar-Seng, Li, Yi, Foo, Jia-Nee, Wang, Wei, Li, Zhi-Jian, Yin, Xian-Yong, Tang, Xue-Qing, Fan, Li, Chen, Jian, Li, Rong-Shan, Wan, Jian-Xin, Liu, Zhang-Suo, and Lou, Tan-Qi

Subjects
DISEASE susceptibility, IGA glomerulonephritis, LOCUS (Genetics), CHINESE people, TUMOR necrosis factors, MAJOR histocompatibility complex, DISEASES
Abstract

We performed a two-stage genome-wide association study of IgA nephropathy (IgAN) in Han Chinese, with 1,434 affected individuals (cases) and 4,270 controls in the discovery phase and follow-up of the top 61 SNPs in an additional 2,703 cases and 3,464 controls. We identified associations at 17p13 (rs3803800, P = 9.40 × 10?11, OR = 1.21; rs4227, P = 4.31 × 10?10, OR = 1.23) and 8p23 (rs2738048, P = 3.18 × 10?14, OR = 0.79) that implicated the genes encoding tumor necrosis factor (TNFSF13) and ?-defensin (DEFA) as susceptibility genes. In addition, we found multiple associations in the major histocompatibility complex (MHC) region (rs660895, P = 4.13 × 10?20, OR = 1.34; rs1794275, P = 3.43 × 10?13, OR = 1.30; rs2523946, P = 1.74 × 10?11, OR = 1.21) and confirmed a previously reported association at 22q12 (rs12537, P = 1.17 × 10?11, OR = 0.78). We also found that rs660895 was associated with clinical subtypes of IgAN (P = 0.003), proteinuria (P = 0.025) and IgA levels (P = 0.047). Our findings show that IgAN is associated with variants near genes involved in innate immunity and inflammation. [ABSTRACT FROM AUTHOR]

Published
2012
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8. Multi-ancestry genome-wide association study of 21,000 cases and 95,000 controls identifies new risk loci for atopic dermatitis.

Author

Paternoster L, Standl M, Waage J, Baurecht H, Hotze M, Strachan DP, Curtin JA, Bønnelykke K, Tian C, Takahashi A, Esparza-Gordillo J, Alves AC, Thyssen JP, den Dekker HT, Ferreira MA, Altmaier E, Sleiman PM, Xiao FL, Gonzalez JR, Marenholz I, Kalb B, Yanes MP, Xu CJ, Carstensen L, Groen-Blokhuis MM, Venturini C, Pennell CE, Barton SJ, Levin AM, Curjuric I, Bustamante M, Kreiner-Møller E, Lockett GA, Bacelis J, Bunyavanich S, Myers RA, Matanovic A, Kumar A, Tung JY, Hirota T, Kubo M, McArdle WL, Henderson AJ, Kemp JP, Zheng J, Smith GD, Rüschendorf F, Bauerfeind A, Lee-Kirsch MA, Arnold A, Homuth G, Schmidt CO, Mangold E, Cichon S, Keil T, Rodríguez E, Peters A, Franke A, Lieb W, Novak N, Fölster-Holst R, Horikoshi M, Pekkanen J, Sebert S, Husemoen LL, Grarup N, de Jongste JC, Rivadeneira F, Hofman A, Jaddoe VW, Pasmans SG, Elbert NJ, Uitterlinden AG, Marks GB, Thompson PJ, Matheson MC, Robertson CF, Ried JS, Li J, Zuo XB, Zheng XD, Yin XY, Sun LD, McAleer MA, O'Regan GM, Fahy CM, Campbell LE, Macek M, Kurek M, Hu D, Eng C, Postma DS, Feenstra B, Geller F, Hottenga JJ, Middeldorp CM, Hysi P, Bataille V, Spector T, Tiesler CM, Thiering E, Pahukasahasram B, Yang JJ, Imboden M, Huntsman S, Vilor-Tejedor N, Relton CL, Myhre R, Nystad W, Custovic A, Weiss ST, Meyers DA, Söderhäll C, Melén E, Ober C, Raby BA, Simpson A, Jacobsson B, Holloway JW, Bisgaard H, Sunyer J, Hensch NMP, Williams LK, Godfrey KM, Wang CA, Boomsma DI, Melbye M, Koppelman GH, Jarvis D, McLean WI, Irvine AD, Zhang XJ, Hakonarson H, Gieger C, Burchard EG, Martin NG, Duijts L, Linneberg A, Jarvelin MR, Noethen MM, Lau S, Hübner N, Lee YA, Tamari M, Hinds DA, Glass D, Brown SJ, Heinrich J, Evans DM, and Weidinger S

Subjects
Case-Control Studies, Dermatitis, Atopic pathology, Humans, Immunity, Innate genetics, Risk Factors, T-Lymphocytes cytology, T-Lymphocytes immunology, T-Lymphocytes metabolism, Dermatitis, Atopic ethnology, Dermatitis, Atopic genetics, Ethnicity genetics, Genetic Loci, Genetic Markers genetics, Genetic Predisposition to Disease, Genome-Wide Association Study, Polymorphism, Single Nucleotide genetics
Abstract

Genetic association studies have identified 21 loci associated with atopic dermatitis risk predominantly in populations of European ancestry. To identify further susceptibility loci for this common, complex skin disease, we performed a meta-analysis of >15 million genetic variants in 21,399 cases and 95,464 controls from populations of European, African, Japanese and Latino ancestry, followed by replication in 32,059 cases and 228,628 controls from 18 studies. We identified ten new risk loci, bringing the total number of known atopic dermatitis risk loci to 31 (with new secondary signals at four of these loci). Notably, the new loci include candidate genes with roles in the regulation of innate host defenses and T cell function, underscoring the important contribution of (auto)immune mechanisms to atopic dermatitis pathogenesis.

Published
2015
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