1. Obstacles and opportunities in translational research.
- Author
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Hörig, Heidi, Marincola, Elizabeth, and Marincola, Francesco M.
- Subjects
- *
RESEARCH , *MEDICINE , *DRUG development , *BIOMARKERS , *THERAPEUTICS - Abstract
Reports on traditional boundaries among basic research, clinical research and patient-oriented research which are yielding to a single, continuous, bidirectional spectrum commonly termed "translational research" or "translational medicine". Definition of guidelines for drug development or for the identification and validation of clinically relevant biomarker; Experimental nonhuman and nonclinical studies conducted with the intent of developing principles for the discovery of new therapeutic strategies; Basic science studies that define the biological effects of therapeutics in humans.
- Published
- 2005
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