Search

Your search keyword '"Dooley, Ruth"' showing total 2 results
Start Over Author "Dooley, Ruth" Journal nature neuroscience
2 results on '"Dooley, Ruth"'

2. Odorant receptor heterodimerization in the olfactory system of Drosophila melanogaster.

Author

Neuhaus, Eva M, Gisselmann, G&aouml;nter, Zhang, Weiyi, Dooley, Ruth, Stärtkuhl, Klemens, and Hatt, Hanns

Subjects
DROSOPHILA melanogaster, NERVOUS system, NEURONS, CELLS, DROSOPHILIDAE, PROTEINS
Abstract

Despite increasing knowledge about dimerization of G-protein-coupled receptors, nothing is known about dimerization in the largest subfamily, odorant receptors. Using a combination of biochemical and electrophysiological approaches, we demonstrate here that odorant receptors can dimerize. DOR83b, an odorant receptor that is ubiquitously expressed in olfactory neurons from Drosophila melanogaster and highly conserved among insect species, forms heterodimeric complexes with other odorant-receptor proteins, which strongly increases their functionality. [ABSTRACT FROM AUTHOR]

Published
2005
Full Text
View/download PDF

Catalog

Books, media, physical & digital resources
See catalog results