1. [Shoshin beriberi provoked by the inhalation of salbutamol].
- Author
-
Groeneveld JH, Geelhoed-Duijvestijn PH, Veldkamp RF, and Baur HJ
- Subjects
- Acidosis, Lactic diagnosis, Acidosis, Lactic etiology, Acute Disease, Administration, Inhalation, Albuterol administration & dosage, Beriberi chemically induced, Beriberi complications, Beriberi drug therapy, Bronchodilator Agents administration & dosage, Cardiac Output, Low diagnosis, Cardiac Output, Low etiology, Humans, Male, Middle Aged, Thiamine Deficiency complications, Thiamine Deficiency drug therapy, Albuterol adverse effects, Beriberi diagnosis, Bronchodilator Agents adverse effects, Thiamine therapeutic use
- Abstract
A 45-year-old male alcoholic with a deficient diet was given salbutamol for exertion-related dyspnoea. After inhalation, he presented with a severe dyspnoea, acrocyanosis, anuria and low blood pressure as well as a respiratory compensated lactate acidosis. Shoshin beriberi was suspected on clinical grounds. The low level of thiamine and the prompt recovery after thiamine repletion confirmed this diagnosis. Shoshin beriberi is an acute, cardiac form of beriberi, which can rapidly result in death due to cardiogenic shock and lactate acidosis. Adrenergic agents can cause a hyperdynamic circulation and thus aggravate the effects of a thiamine deficiency.
- Published
- 2003