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Start Over Author "Tarnow L" Journal nephrology dialysis transplantation
12 results on '"Tarnow L"'

2. Elevated NT-proBNP and coronary calcium score in relation to coronary artery disease in asymptomatic type 2 diabetic patients with elevated urinary albumin excretion rate

Author

Reinhard, H., primary, Hansen, P. R., additional, Persson, F., additional, Tarnow, L., additional, Wiinberg, N., additional, Kjaer, A., additional, Petersen, C. L., additional, Winther, K., additional, Parving, H.-H., additional, Rossing, P., additional, and Jacobsen, P. K., additional

Published
2011
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7. Plasma renin and prorenin and renin gene variation in patients with insulin-dependent diabetes mellitus and nephropathy.

Author

Deinum, J, Tarnow, L, van Gool, JM, de Bruin, RA, Derkx, FHM, Schalekamp, MADH, and Parving, H-H

Abstract

Background. The most striking abnormality in the renin-angiotensin system in diabetic nephropathy (DN) is increased plasma prorenin. Renin is thought to be low or normal in DN. In spite of altered (pro)renin regulation the renin gene has not been studied for contribution to the development of DN. [ABSTRACT FROM PUBLISHER]

Published
1999
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8. Diabetic microvascular complications are not associated with two polymorphisms in the GLUT-1 and PC-1 genes regulating glucose metabolism in Caucasian type 1 diabetic patients.

Author

Tarnow, L, Grarup, N, Hansen, T, Parving, H H, and Pedersen, O

Abstract

An XbaI polymorphism in the gene encoding the glucose transporter, GLUT-1, is associated with development of diabetic nephropathy in Chinese type 2 diabetic patients. In addition, an amino acid variant (K121Q) in the gene encoding the glycoprotein plasma cell differentiating antigen (PC-1), a specific inhibitor of insulin receptor signalling, has been reported to predict a faster progression of nephropathy in Italian and British type 1 diabetic patients.

Published
2001
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9. Genetic polymorphisms of the renin-angiotensin system and complications of insulin-dependent diabetes mellitus.

Author

van Ittersum, F J, de Man, A M, Thijssen, S, de Knijff, P, Slagboom, E, Smulders, Y, Tarnow, L, Donker, A J, Bilo, H J, and Stehouwer, C D

Abstract

Patients with insulin-dependent diabetes mellitus (IDDM) have a high risk of developing diabetic nephropathy, retinopathy and cardiovascular diseases. The contribution of gene polymorphisms of the renin angiotensin system to these complications is controversial and may differ among populations.

Published
2000
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10. Plasminogen activator inhibitor-1 and apolipoprotein E gene polymorphisms and diabetic angiopathy.

Author

Tarnow, L, Stehouwer, C D, Emeis, J J, Poirier, O, Cambien, F, Hansen, B V, and Parving, H H

Abstract

A point mutation in the plasminogen activator inhibitor-1 (PAI-1) gene and a three-allelic variation in the apolipoprotein-E (ApoE) gene have been suggested as risk factors for the development of diabetic micro- and macrovascular complications.

Published
2000
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12. The Trp64Arg amino acid polymorphism of the β3-adrenergic receptor gene does not contribute to the genetic susceptibility of diabetic microvascular complications in Caucasian type 1 diabetic patients.

Author

Tarnow, L, Urhammer, SA, Mottlau, B, Hansen, BV, Pederson, O, and Parving, H-H

Abstract

Objective.The β3-adrenergic receptor is involved in regulation of microvascular blood flow. A missense mutation (Trp64Arg) in the β3-adrenergic receptor gene has been suggested as a risk factor for proliferative retinopathy in Japanese type 2 diabetic patients. The aim of the present study was to evaluate the contribution of this polymorphism to the development of microangiopathic complications in Caucasian type 1 diabetic patients. [ABSTRACT FROM PUBLISHER]

Published
1999
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