Search

I deem it a privilege to have been asked by Prof. P. Sarat Chandra, Editor, to write a Commentary on the paper mentioned above by Prof. Dastur et al., published half a century ago. Neurol India 2018;66:301-3. 3 Dastur DK, Lalitha VS, Udani PM, Parekh U. The brain and meninges in tuberculous meningitis-Gross pathology in 100 cases and pathogenesis. New Delhi: Indian Academy of Medical Sciences; 1973. p. 269-75. 66 Tandon PN, Pande A. (a) Tuberculosis of the central nervous system, (b) Tuberculous meningitis. [Extracted from the article]

The article discusses the function of the neural stem cells, astrocytes and microglia in physiological and pathological states of the nervous system. It reveals that adults have neural stem cells in some parts of the brain which can help replace damaged brain cells in mammals. It has been claimed that the microglia play an important role in neuroinflammation associated with neurodegeneration. In addition, astrocytes are needed for normal synaptogenesis and synaptic stability.