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The article offers information on neuroinflammation along with its presence in different developmental disorders such as autism. Topics discussed include manifestation of neuroinflammation process through microglia along astrocytes presence; association of microglia with proinflammatory cytokines along with analysis of several factors such as prostaglandin (PGE); and regulation of an inflammation conditions through neural cell adhesion molecule (NCAM).

The article discusses the function of the neural stem cells, astrocytes and microglia in physiological and pathological states of the nervous system. It reveals that adults have neural stem cells in some parts of the brain which can help replace damaged brain cells in mammals. It has been claimed that the microglia play an important role in neuroinflammation associated with neurodegeneration. In addition, astrocytes are needed for normal synaptogenesis and synaptic stability.