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Your search keyword '"MESH: Brain Mapping"' showing total 3 results
Start Over Descriptor "MESH: Brain Mapping" Journal neuropsychologia
3 results on '"MESH: Brain Mapping"'

1. Effortless control: executive attention and conscious feeling of mental effort are dissociable

Author

Stanislas Dehaene, Damien Galanaud, Marie-Odile Habert, Laurent D. Cohen, Jean-Claude Willer, Lionel Naccache, Elodie Guichart-Gomez, Neuroimagerie cognitive (LCogn), Université Paris-Sud - Paris 11 (UP11)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Institut National de la Santé et de la Recherche Médicale (INSERM), Service Hospitalier Frédéric Joliot (SHFJ), Université Paris-Saclay-Direction de Recherche Fondamentale (CEA) (DRF (CEA)), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA), CEntre de REcherches en MAthématiques de la DEcision (CEREMADE), Université Paris Dauphine-PSL, Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Centre National de la Recherche Scientifique (CNRS), Service de Neurologie [CHU Pitié-Salpêtrière], IFR70-CHU Pitié-Salpêtrière [AP-HP], Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP), Laboratoire d'Imagerie Fonctionnelle (LIF), Université Pierre et Marie Curie - Paris 6 (UPMC)-IFR14-IFR49-Institut National de la Santé et de la Recherche Médicale (INSERM), Service de Médecine nucléaire [CHU Pitié-Salpétrière], CHU Pitié-Salpêtrière [AP-HP], Imagerie médicale et quantitative, Institut National de la Santé et de la Recherche Médicale (INSERM), Service de Neuroradiologie [CHU Pitié-Salpêtrière], Centre de résonance magnétique biologique et médicale (CRMBM), Aix Marseille Université (AMU)-Assistance Publique - Hôpitaux de Marseille (APHM)-Centre National de la Recherche Scientifique (CNRS), Physiologie et physiopathologie de la motricité chez l'homme, Université Pierre et Marie Curie - Paris 6 (UPMC)-IFR70-Institut National de la Santé et de la Recherche Médicale (INSERM), Fédération des Pathologies du Sommeil, Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-CHU Pitié-Salpêtrière [AP-HP], Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP), Direction de Recherche Fondamentale (CEA) (DRF (CEA)), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Université Paris-Saclay, Centre National de la Recherche Scientifique (CNRS)-Université Paris Dauphine-PSL, Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL), Sorbonne Université (SU)-Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Sorbonne Université (SU)-Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP), Service de médecine nucléaire [CHU Pitié-Salpétrière], Assistance Publique - Hôpitaux de Marseille (APHM)-Aix Marseille Université (AMU)-Centre National de la Recherche Scientifique (CNRS), Sorbonne Université (SU)-Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Sorbonne Université (SU), Service de neurologie 1 [CHU Pitié-Salpétrière], and Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Sorbonne Université (SU)

Subjects
Cingulate cortex, Emotions, MESH: Frontal Lobe, Neuropsychological Tests, Choice Behavior, Brain mapping, MESH: Linear Models, Developmental psychology, Behavioral Neuroscience, Mental Processes, 0302 clinical medicine, Attention, Evoked Potentials, MESH: Mental Processes, MESH: Brain Mapping, media_common, Brain Mapping, MESH: Middle Aged, 05 social sciences, Electroencephalography, MESH: Neuropsychological Tests, Cognition, Galvanic Skin Response, MESH: Magnetic Resonance Imaging, Cine, Middle Aged, MESH: Case-Control Studies, Frontal Lobe, MESH: Evoked Potentials, MESH: Photic Stimulation, medicine.anatomical_structure, Feeling, MESH: Galvanic Skin Response, Female, Psychology, Somatic marker hypothesis, Cognitive psychology, Adult, Stroop Paradigm, Cognitive Neuroscience, media_common.quotation_subject, Magnetic Resonance Imaging, Cine, Experimental and Cognitive Psychology, MESH: Psychomotor Performance, MESH: Choice Behavior, behavioral disciplines and activities, 050105 experimental psychology, 03 medical and health sciences, MESH: Electroencephalography, Reaction Time, medicine, Humans, 0501 psychology and cognitive sciences, Anterior cingulate cortex, MESH: Emotions, MESH: Attention, MESH: Humans, [SDV.BA.MVSA]Life Sciences [q-bio]/Animal biology/Veterinary medicine and animal Health, MESH: Adult, MESH: Reaction Time, MESH: Cognition Disorders, Brain Injuries, Case-Control Studies, MESH: Brain Injuries, Linear Models, Consciousness, Cognition Disorders, MESH: Female, Photic Stimulation, Psychomotor Performance, 030217 neurology & neurosurgery
Abstract

International audience; Recruitment of executive attention is normally associated to a subjective feeling of mental effort. Here we investigate the nature of this coupling in a patient with a left mesio-frontal cortex lesion including the anterior cingulate cortex (ACC), and in a group of comparison subjects using a Stroop paradigm. We show that in normal subjects, subjective increases in effort associated with executive control correlate with higher skin-conductance responses (SCRs). However, our patient experienced no conscious feeling of mental effort and showed no SCR, in spite of exhibiting normal executive control, and residual right anterior cingulate activity measured with event-related potentials (ERPs). Finally, this patient demonstrated a pattern of impaired behavior and SCRs in the Iowa gambling task-elaborated by Damasio, Bechara and colleagues-replicating the findings reported by these authors for other patients with mesio-frontal lesions. Taken together, these results call for a theoretical refinement by revealing a decoupling between conscious cognitive control and consciously reportable feelings. Moreover, they reveal a fundamental distinction, observed here within the same patient, between the cognitive operations which are depending on normal somatic marker processing, and those which are withstanding to impairments of this system.

Published
2005
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2. Neural correlates of implicit object identification

Author

Muriel Boucart, M. E. Meyer, Glyn W. Humphreys, Jack R. Foucher, Delphine Pins, Laboratoire de Neurosciences Fonctionnelles et Pathologies (LNFP), Université de Lille, Droit et Santé-Centre National de la Recherche Scientifique (CNRS), Laboratoire des Solides Irradiés (LSI), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Centre National de la Recherche Scientifique (CNRS)-École polytechnique (X), Laboratoire de chimie et biochimie des substances naturelles, Muséum national d'Histoire naturelle (MNHN)-Centre National de la Recherche Scientifique (CNRS), Liquides Ioniques et Interfaces Chargées (LI2C), Université Pierre et Marie Curie - Paris 6 (UPMC)-Ecole Superieure de Physique et de Chimie Industrielles de la Ville de Paris (ESPCI Paris), Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Centre National de la Recherche Scientifique (CNRS), Laboratoire de Psychopathologie et de Pharmacologie de la Cognition, IFR37-Institut National de la Santé et de la Recherche Médicale (INSERM)-Institut National de la Santé et de la Recherche Médicale (INSERM), Lithography Laboratory, Commissariat à l'énergie atomique et aux énergies alternatives (CEA), Service d'Hépato-Gastro-Entérologie, CHU Bordeaux [Bordeaux]-Hôpital Saint-André, Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-École polytechnique (X)-Centre National de la Recherche Scientifique (CNRS), and Boucart, Muriel

Subjects
Male, MESH: Evoked Potentials, Visual, genetic structures, MESH: Frontal Lobe, MESH: Semantics, MESH: Magnetic Resonance Imaging, Behavioral Neuroscience, Mental Processes, 0302 clinical medicine, Reference Values, Semantic memory, MESH: Brain Mapping, MESH: Mental Processes, Visual Cortex, media_common, Cerebral Cortex, Brain Mapping, Orientation (computer vision), 05 social sciences, MESH: Reference Values, Magnetic Resonance Imaging, MESH: Recognition (Psychology), Temporal Lobe, Frontal Lobe, Semantics, medicine.anatomical_structure, Female, [SDV.NEU]Life Sciences [q-bio]/Neurons and Cognition [q-bio.NC], Psychology, psychological phenomena and processes, Cognitive psychology, Adult, Cognitive Neuroscience, media_common.quotation_subject, Experimental and Cognitive Psychology, behavioral disciplines and activities, 050105 experimental psychology, 03 medical and health sciences, Perception, medicine, Humans, MESH: Temporal Lobe, MESH: Form Perception, 0501 psychology and cognitive sciences, Neural correlates of consciousness, Communication, MESH: Humans, Fusiform gyrus, business.industry, MESH: Visual Cortex, Recognition, Psychology, MESH: Adult, Object (computer science), MESH: Cerebral Cortex, MESH: Male, Form Perception, Visual cortex, MESH: Nerve Net, Evoked Potentials, Visual, Nerve Net, business, MESH: Female, 030217 neurology & neurosurgery
Abstract

International audience; The present study sought to assess neural correlates of implicit identification of objects by means of fMRI, using tasks that require matching of the physical properties of objects. Behavioural data suggests that there is automatic access to object identity when observers attend to a physical property of the form of an object (e.g. the object's orientation) and no evidence for semantic processing when subjects attend to colour. We evaluated whether, in addition to neural areas associated with decisions to specific perceptual properties, areas associated with access to semantic information were activated when tasks demanded processing of the global configuration of pictures. We used two perceptual matching tasks based on the global orientation or on the colour of line drawings. Our results confirmed behavioural data. Activations in the inferior occipital cortex, fusiform and inferior temporal gyri in both tasks (orientation and colour) account for perceptual and structural processing involved in each task. In contrast, activations in the posterior and medial parts of the fusiform gyrus, shown to be involved in explicit semantic judgements, were more pronounced in the orientation-matching task, suggesting that semantic information from the pictures is processed in an implicit way even when not required by the task. Thus, this study suggests that cortical regions usually involved in explicit semantic processing are also activated when implicit processing of objects occurs.

Published
2004
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3. Three-dimensional surface mapping of hippocampal atrophy progression from MCI to AD and over normal aging as assessed using voxel-based morphometry

Author

Marine Fouquet, Florence Mézenge, Grégoria Kalpouzos, Gaël Chételat, V. de la Sayette, Francis Eustache, I. Denghien, Brigitte Landeau, Jean-Claude Baron, Fausto Viader, Béatrice Desgranges, Laboratoire de Neuropsychologie, Université de Caen Normandie (UNICAEN), Normandie Université (NU)-Normandie Université (NU)-École pratique des hautes études (EPHE), Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Institut National de la Santé et de la Recherche Médicale (INSERM), IFR49 - Neurospin - CEA, Commissariat à l'énergie atomique et aux énergies alternatives (CEA), Centre de Recherches sur la Cognition et l'Apprentissage (CeRCA), Centre National de la Recherche Scientifique (CNRS)-Université de Tours-Université de Poitiers, Department of Clinical Neurosciences [Cambridge], University of Cambridge [UK] (CAM), Eustache, Francis, Université de Poitiers-Université de Tours (UT)-Centre National de la Recherche Scientifique (CNRS), and Normandie Université (NU)-Normandie Université (NU)-École Pratique des Hautes Études (EPHE)

Subjects
Male, MESH: Psychiatric Status Rating Scales, Aging, MESH: Hippocampus, Hippocampus, Normal Aging, Hippocampal formation, Neuropsychological Tests, Alzheimer's Disease, MESH: Magnetic Resonance Imaging, Behavioral Neuroscience, 0302 clinical medicine, Degenerative disease, MESH: Aged, 80 and over, MESH: Aging, 10. No inequality, MESH: Brain Mapping, MESH: Aged, Aged, 80 and over, 0303 health sciences, education.field_of_study, Brain Mapping, MESH: Middle Aged, Subiculum, MESH: Neuropsychological Tests, Middle Aged, Magnetic Resonance Imaging, Disease Progression, MESH: Disease Progression, [SDV.NEU]Life Sciences [q-bio]/Neurons and Cognition [q-bio.NC], Female, Alzheimer's disease, Psychology, Adult, Mild Cognitive Impairment, Longitudinal Imaging, Cognitive Neuroscience, Population, Experimental and Cognitive Psychology, MESH: Imaging, Three-Dimensional, MESH: Atrophy, 03 medical and health sciences, Atrophy, Imaging, Three-Dimensional, Alzheimer Disease, medicine, Humans, [SDV.NEU] Life Sciences [q-bio]/Neurons and Cognition [q-bio.NC], education, 030304 developmental biology, Aged, Psychiatric Status Rating Scales, MESH: Humans, MESH: Adult, Voxel-based morphometry, medicine.disease, MESH: Male, Structural MRI, MESH: Cognition Disorders, nervous system, Hippocampal Subfields, Cognition Disorders, Neuroscience, Voxel-Based Morphometry, MESH: Female, 030217 neurology & neurosurgery, MESH: Alzheimer Disease
Abstract

International audience; The hippocampus is the brain structure of highest and earliest structural alteration in Alzheimer's disease (AD). New developments in neuroimaging methods recently made it possible to assess the respective involvement of the different hippocampal subfields by mapping atrophy on a 3D hippocampal surface view. In this longitudinal study on patients with mild cognitive impairment (MCI), we used such an approach to map the profile of hippocampal atrophy and its progression over an 18-month follow-up period in rapid converters to AD and "non-converters" compared to age-matched controls. For the sake of comparison, we also assessed the profile of hippocampal atrophy associated with AD and with increasing age in a healthy control population ranging from young adult to elderly. We found major involvement of the lateral part of the superior hippocampus mainly corresponding to the CA1 subfield in MCI and AD while increasing age was mainly associated with subiculum atrophy in the healthy population. Moreover, the CA1 subfield also showed highest atrophy rates during follow-up, in both rapid converters and "non-converters" although increased effects were observed in the former group. This study emphasizes the differences between normal aging and AD processes leading to hippocampal atrophy, pointing to a specific AD-related CA1 involvement while subiculum atrophy would represent a normal aging process. Our findings also suggest that the degree of hippocampal atrophy, more than its spatial localization, predicts rapid conversion to AD in patients with MCI.

Published
2007
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