1. Immunologic pathogenesis of multiple sclerosis
- Author
-
Ning Ji, Min-Fang Guo, and Cun-Gen Ma
- Subjects
Autoimmune disease ,medicine.medical_specialty ,Neurology ,Physiology ,General Neuroscience ,Multiple sclerosis ,Autoantibody ,General Medicine ,Human physiology ,Biology ,medicine.disease ,Pathogenesis ,Immunology ,medicine ,Etiology - Abstract
Multiple sclerosis (MS) is an autoimmune disease. The etiology and pathogenesis of MS remain unclear. At present, there are substantial evidences to support the hypothesis that genetics plays a crucial role. The people who have genetic predisposing genes easily develop immune-mediated disorder, probably in conjunction with environmental factors. The aim of this review is to describe recent observations regarding the immunologic pathogenesis of MS.
- Published
- 2008