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A 39-year-old woman in the first trimester of her first pregnancy was seen in the obstetrics and gynecology clinic of this hospital at 14 weeks of gestation because of persistent fevers. She had recently traveled to Africa to adopt a child. In the interval between returning home and becoming ill, she became pregnant. On examination, there was a maculopapular rash over the trunk, arms, and legs, as well as a slightly enlarged liver. Sequential ultrasound examinations showed an apparently normal fetus.

A 35-year-old woman in her second pregnancy was found to have hypertension and glycosuria at 17 weeks' gestation, which persisted despite medication. She was admitted to the hospital. She had had gestational diabetes during her first pregnancy. Serum electrolytes were normal except for a potassium level of 2.6 mmol per liter. Additional laboratory testing and a diagnostic procedure were performed.

Presentation of Case A newborn boy was admitted to the hospital because of respiratory distress and a "ground-glass" appearance on an x-ray film of the chest. The child was born at 38 1/2 weeks of the first pregnancy of a mother 26 years of age whose blood type was O, Rh positive. The child was conceived while his father, 30 years old, was taking doxorubicin for treatment of a relapse of acute lymphocytic leukemia of three years' duration. An amniocentesis, performed at approximately 13 weeks of gestation, was said to show a translocation of chromosomes 16 and 9. Repeated ultrasonographic . . .

The medical mystery in the June 21 issue1 involved a 28-year-old woman with a 1-year history of high blood pressure that was diagnosed during her first pregnancy. In addition to an elevated blood p...

Presentation of Case A five-year-old boy was admitted to the hospital because of hypospadias. He was born of a first pregnancy, which was complicated by toxemia. Labor was induced one month prematurely; the birth weight was 2.1 kg. Perineoscrotal hypospadias was observed at birth. A karyotype showed a normal male pattern. At the age of 16 months an intravenous pyelographic examination, performed elsewhere, was reported to be negative. A chordee was repaired in another hospital. Three and a half months before admission he was first seen at this hospital. The height was 105.4 cm (10th percentile), the weight 17.3 kg . . .

Presentation of Case A 27-year-old woman was admitted to the hospital at 19 weeks of gestation because of a fetal abnormality. The patient was in good health and took no medication during her pregnancy except for a multivitamin tablet. There was no history of abnormal bleeding, infection, or radiation exposure. The first pregnancy resulted in a spontaneous abortion in the first trimester. An ultrasound examination performed during labor in the second pregnancy revealed absence of a normal skull and a hydrocephalic sac. The offspring was a hydrocephalic stillborn; the parents were told of abnormalities of the arms, but no autopsy . . .

Presentation of Case First admission. A 6 1/2-year-old boy was admitted to the hospital because of hematuria. He was born of a 23-year-old mother with an uncomplicated first pregnancy and delivery....

Presentation of Case A 29-year-old woman was admitted to the hospital because of increasing cough and dyspnea. She was well until nine years earlier, when mild dyspnea and a chronic cough developed during her first pregnancy and gradually increased in severity. Ten months before admission the dyspnea became more marked. Five months before entry the cough and dyspnea worsened acutely, and arthralgia and fever developed. She was admitted to this hospital. She had lost 18 kg in weight in three years, including 9 kg during the last six months. Examination revealed dyspnea, crackles, rhonchi, and wheezes in both lungs, shotty . . .

Presentation of Case A 6 1/2-year-old girl was admitted to the hospital because of sexual precocity. She was born of an uncomplicated, full-term delivery of the first pregnancy in a mother aged 20 ...

Presentation of Case A five-week-old girl was admitted to the hospital because of fever and petechiae. She was born of a full-term first pregnancy and normal delivery to a white mother of blood group A positive. The mother did not smoke or use alcohol or medications other than multivitamins during the pregnancy and experienced no complications. The fetal membranes ruptured one hour before initial uterine contractions, and labor lasted seven hours. The birth weight was 3.5 kg, and the Apgar score was 9/9. Macular, erythematous patches were observed on the right thigh and head at birth. The child was discharged . . .

Presentation of Case A 29-year-old woman was admitted to the hospital because of a left thoracoabdominal mass. She was well until 18 months earlier, when she began to experience discomfort in the left flank during her first pregnancy. Three months later her son was delivered. The child was breast-fed for the first five months, and then bottle feedings were substituted. Lactation persisted, with amenorrhea. The discomfort in the left flank progressed to local pain and tenderness and was accompanied by a marked decrease in libido. Six months before entry an obstetrician administered a single dose of medroxyprogesterone acetate, which was . . .

Presentation of Case A 2 1/2 -year-old boy was admitted to the hospital because of respiratory distress. He was born of an uncomplicated first pregnancy of a 22-year-old mother. The presence of Dow...

Presentation of Case A 26-year-old woman was admitted to the hospital because of renal failure. Two and a half months before admission an uncomplicated first pregnancy eventuated in the normal deli...