Search

Your search keyword '"Hauser, Stephen"' showing total 15 results
Start Over Author "Hauser, Stephen" Journal new england journal of medicine
15 results on '"Hauser, Stephen"'

3. Ofatumumab versus Teriflunomide in Multiple Sclerosis

Author

Hauser, Stephen L., primary, Bar-Or, Amit, additional, Cohen, Jeffrey A., additional, Comi, Giancarlo, additional, Correale, Jorge, additional, Coyle, Patricia K., additional, Cross, Anne H., additional, de Seze, Jerome, additional, Leppert, David, additional, Montalban, Xavier, additional, Selmaj, Krzysztof, additional, Wiendl, Heinz, additional, Kerloeguen, Cecile, additional, Willi, Roman, additional, Li, Bingbing, additional, Kakarieka, Algirdas, additional, Tomic, Davorka, additional, Goodyear, Alexandra, additional, Pingili, Ratnakar, additional, Häring, Dieter A., additional, Ramanathan, Krishnan, additional, Merschhemke, Martin, additional, and Kappos, Ludwig, additional

Published
2020
Full Text
View/download PDF

4. Ocrelizumab versus Interferon Beta-1a in Relapsing Multiple Sclerosis

Author

Hauser, Stephen L., primary, Bar-Or, Amit, additional, Comi, Giancarlo, additional, Giovannoni, Gavin, additional, Hartung, Hans-Peter, additional, Hemmer, Bernhard, additional, Lublin, Fred, additional, Montalban, Xavier, additional, Rammohan, Kottil W., additional, Selmaj, Krzysztof, additional, Traboulsee, Anthony, additional, Wolinsky, Jerry S., additional, Arnold, Douglas L., additional, Klingelschmitt, Gaelle, additional, Masterman, Donna, additional, Fontoura, Paulo, additional, Belachew, Shibeshih, additional, Chin, Peter, additional, Mairon, Nicole, additional, Garren, Hideki, additional, and Kappos, Ludwig, additional

Published
2017
Full Text
View/download PDF

5. Ocrelizumab versus Placebo in Primary Progressive Multiple Sclerosis

Author

Montalban, Xavier, primary, Hauser, Stephen L., additional, Kappos, Ludwig, additional, Arnold, Douglas L., additional, Bar-Or, Amit, additional, Comi, Giancarlo, additional, de Seze, Jérôme, additional, Giovannoni, Gavin, additional, Hartung, Hans-Peter, additional, Hemmer, Bernhard, additional, Lublin, Fred, additional, Rammohan, Kottil W., additional, Selmaj, Krzysztof, additional, Traboulsee, Anthony, additional, Sauter, Annette, additional, Masterman, Donna, additional, Fontoura, Paulo, additional, Belachew, Shibeshih, additional, Garren, Hideki, additional, Mairon, Nicole, additional, Chin, Peter, additional, and Wolinsky, Jerry S., additional

Published
2017
Full Text
View/download PDF

7. B-Cell Depletion with Rituximab in Relapsing–Remitting Multiple Sclerosis

Author

Hauser, Stephen L., primary, Waubant, Emmanuelle, additional, Arnold, Douglas L., additional, Vollmer, Timothy, additional, Antel, Jack, additional, Fox, Robert J., additional, Bar-Or, Amit, additional, Panzara, Michael, additional, Sarkar, Neena, additional, Agarwal, Sunil, additional, Langer-Gould, Annette, additional, and Smith, Craig H., additional

Published
2008
Full Text
View/download PDF

8. Case 38-1990

Author

Cabot, Richard C., primary, Scully, Robert E., additional, Mark, Eugene J., additional, McNeely, William F., additional, McNeely, Betty U., additional, Hauser, Stephen L., additional, Shahani, Bhagwan, additional, and Hedley-Whyte, E. Tessa, additional

Published
1990
Full Text
View/download PDF

9. Rituximab in Relapsing–Remitting Multiple Sclerosis.

Author

Hauser, Stephen L., Waubant, Emmanuelle, and Bar-Or, Amit

Subjects
*LETTERS to the editor, *MULTIPLE sclerosis
Abstract

Stephen L. Hauser, Emmanuelle Waubant and Amit Bar-Or respond to a letter to the editor about their article "B Cell Depletion With Rituximab in Relapsing-Remitting Multiple Sclerosis" in the February 14, 2008 issue.

Published
2008
Full Text
View/download PDF

12. Genomewide Study of Multiple Sclerosis.

Author

Hafler, David A., Compston, Alastair, and Hauser, Stephen L.

Subjects
*MULTIPLE sclerosis, *LETTERS to the editor
Abstract

A reply by David A. Hafler, Alastair Compston and Stephen L. Hauser to letters to the editor about their article “Risk alleles for multiple sclerosis identified by a genomewide study,” in the August 30, 2007 issue is presented.

Published
2007
Full Text
View/download PDF

15. Risk alleles for multiple sclerosis identified by a genomewide study.

Author

Hafler DA, Compston A, Sawcer S, Lander ES, Daly MJ, De Jager PL, de Bakker PI, Gabriel SB, Mirel DB, Ivinson AJ, Pericak-Vance MA, Gregory SG, Rioux JD, McCauley JL, Haines JL, Barcellos LF, Cree B, Oksenberg JR, and Hauser SL

Subjects
Adolescent, Adult, Aged, Alleles, Female, Genetic Predisposition to Disease, Genome, Human, HLA-DR alpha-Chains, Humans, Linkage Disequilibrium, Male, Middle Aged, Mutation, Oligonucleotide Array Sequence Analysis, Polymorphism, Single Nucleotide, Risk Factors, HLA-DR Antigens genetics, Interleukin-2 Receptor alpha Subunit genetics, Interleukin-7 Receptor alpha Subunit genetics, Multiple Sclerosis genetics
Abstract

Background: Multiple sclerosis has a clinically significant heritable component. We conducted a genomewide association study to identify alleles associated with the risk of multiple sclerosis., Methods: We used DNA microarray technology to identify common DNA sequence variants in 931 family trios (consisting of an affected child and both parents) and tested them for association. For replication, we genotyped another 609 family trios, 2322 case subjects, and 789 control subjects and used genotyping data from two external control data sets. A joint analysis of data from 12,360 subjects was performed to estimate the overall significance and effect size of associations between alleles and the risk of multiple sclerosis., Results: A transmission disequilibrium test of 334,923 single-nucleotide polymorphisms (SNPs) in 931 family trios revealed 49 SNPs having an association with multiple sclerosis (P<1x10(-4)); of these SNPs, 38 were selected for the second-stage analysis. A comparison between the 931 case subjects from the family trios and 2431 control subjects identified an additional nonoverlapping 32 SNPs (P<0.001). An additional 40 SNPs with less stringent P values (<0.01) were also selected, for a total of 110 SNPs for the second-stage analysis. Of these SNPs, two within the interleukin-2 receptor alpha gene (IL2RA) were strongly associated with multiple sclerosis (P=2.96x10(-8)), as were a nonsynonymous SNP in the interleukin-7 receptor alpha gene (IL7RA) (P=2.94x10(-7)) and multiple SNPs in the HLA-DRA locus (P=8.94x10(-81))., Conclusions: Alleles of IL2RA and IL7RA and those in the HLA locus are identified as heritable risk factors for multiple sclerosis., (Copyright 2007 Massachusetts Medical Society.)

Published
2007
Full Text
View/download PDF

Catalog

Books, media, physical & digital resources
See catalog results