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Your search keyword '"Mani, Geeta Sai"' showing total 4 results
Start Over Author "Mani, Geeta Sai" Journal new journal of chemistry
4 results on '"Mani, Geeta Sai"'

4. Iodine-promoted one-pot synthesis of 1,3,4-oxadiazole scaffolds via sp3 C–H functionalization of azaarenes.

Author

Mani, Geeta Sai, Donthiboina, Kavitha, Shankaraiah, Nagula, and Kamal, Ahmed

Subjects
*IODINE, *FUNCTIONAL groups, *AMINATION
Abstract

An efficient iodine-mediated one-pot synthetic protocol for the synthesis of 2,5-disubstituted 1,3,4-oxadiazole scaffolds has been developed via sp3 C–H functionalization. Gratifyingly, this method involves oxidative amination with concomitant base-mediated cyclization of methylhetarenes and acylhydrazines by employing iodine and Cs2CO3. The key features of the present method include good functional group tolerance, a clean protocol, metal-free conditions and high yields, making this protocol an attractive strategy towards the synthesis of bioactive molecules and their key building blocks. [ABSTRACT FROM AUTHOR]

Published
2019
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