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This is the first example of the construction of harmaline-based spiropolycyclic scaffolds using harmaline-based N–C synthons and evaluation of 3cb as an anticancer agent.

Herein a previously unreported trimethylindolenines serving as useful C-N synthons in [3+2] cycloaddition reactions of donor-acceptor 3-isothiocyanato oxindoles to build a library of spiro[oxindole-thioxoimidazolidine-indoline] hybrids is described. A wide range...

This is the combination of three key pharmacophores through bispiro quaternary carbon atoms and evaluation of their anticancer activity.

Effective excited state modulation of organic frameworks based on 2,4,6-triphenyl-1,3,5-triazine and carbazole derivatives through ortho-positioned linking models has been successfully realized, which will pave the way toward effective synthesis of organic blue light emitters.

The first example of 3-vinyl oxindole-chromones in the ring opening and recyclization reaction.

A highly efficient synthesis of structurally diverse ortho-acylphenol–diindolylmethane hybrids 3 using carboxylic acid-activated chromones as versatile synthetic building blocks is reported here for the first time, through 1,4-nucleophilic addition and followed by a decarboxylation and pyrone ring opening reaction process.

The first example of the introduction of a spiroindanedione moiety into a spirobutyrolactone framework.

A new type of bifunctional 3C synthon, a chromone–indanedione precursor, was employed for diastereoselective Michael/Michael cycloaddition with methyleneindolinones to generate a series of potentially bioactive bispiro-[chromanocyclopentane-oxindole-indanedione] frameworks with skeletal diversity in a single operation. This reaction exhibited good substrate tolerance and gave the desired products in moderate to good yields with high diastereoselectivities via an endo-transition state (up to 78% yield and >20 : 1 diastereomeric ratio). In particular, this reaction is the first example of using a chromone–indanedione precursor as a bifunctional 3C synthon, the first example of the construction of bispiro-chromanocyclopentanes, and also the first example of the introduction of a chromanocyclopentane moiety into spiroindanone frameworks, which might be valuable in medicinal chemistry.

Here, a nanocomposite functional coating consisting of poly(sulfobetaine methacrylate)–vinyltrimethoxysilane–silica (PSBMA@VTMO@silica) hybrid nanoparticles and a combined adhesive of tannic acid (TA) and polyethylene glycol (PEG) was successfully developed through a facile deposition method, and is able to effectively block the adhesion of proteins and subsequent biofouling deposition. The PSBMA@VTMO@silica hybrid nanoparticles could endow the functional coating with high roughness, hydrophilicity and excellent abrasion-resistant properties, and the TA–PEG composite adhesive could be used as a bridge connecting the hybrid nanoparticles and the substrate to ensure the robustness and durability of the coating. Benefiting from these, the as-obtained coating not only is highly resistant to the fouling organisms but also exhibits high stability in harsh environments (for example, it maintained stable hydrophilicity for longer than 40 days in artificial seawater and still possessed good anti-adhesion of proteins after 12 sandpaper abrasion cycles). Additionally, the versatility of this approach was confirmed by successful application to other materials, such as nylon boards, polyethylene sheets and stainless steel foils. Overall, this work enriches the exploration of feasible, stable, and effective marine antifouling coatings under environmentally friendly conditions.

Three D–π–A porphyrin sensitizers with different electronegative moieties (2,4,6-triphenyl-1,3,5-triazine, carbazole and triphenylamine) attached at the meso-position were designed and synthesized for monolithic dye-sensitized solar cells based on mesoscopic carbon counter electrodes. The effects of these different electronegative moieties on the photophysical, electrochemical and accordingly photovoltaic performance of the corresponding devices were investigated systematically. Electrochemical measurements indicate that the HOMO and LUMO energy levels could be tuned through the introduction of different electronegative groups onto the backbone of D–π–A porphyrin molecules. Current–voltage characteristics indicate that the Jsc and Voc of the DSSCs based on WH-C3, WH-C4 and WH-C5 increase as the electron-donating ability of their donors enhance in the order of WH-C3 < WH-C4 < WH-C5 and WH-C5-sensitized cells showed the best photovoltaic performance: a short circuit photocurrent density (Jsc) of 11.43 mA cm−2, an open circuit voltage (Voc) of 633.84 mV, and a fill factor (FF) of 0.69, corresponding to an overall conversion efficiency (η) of 5.00%.

Six Co(II) and Mn(II) coordination polymers, [Co(BIMB)(AIP)]n (1), [Co(BIMB)0.5(H2O)(AIP)]n (2), [Co(BMIB)0.5(AIP)]n·(H2O)n (3), [Mn2(BIMB)2(AIP)2]n (4), [Mn(BMIB)(H2O)2(AIP)]n·(DMF)n (5) and [Mn(BIMB)0.5(PAIP)]n·(H2O)n (6) (AIP = 5-aminoisophthalate, PAIP = 5-(2-pyridylmethyl)aminoisophthalate, BIMB = 1,4-bis(imidazol-1-yl-methyl)benzene and BMIB = 1,4-bis(2-methylimidazol-1-yl-methyl)benzene), were synthesized and characterized. AIP in 1–5 originates from the in situ deprotection of 5-(4-oxopentan-2-ylideneamino)isophthalic acid in the synthetic process. Complex 1 is a 2D → 3D interdigitating network, and hydrogen bonds between the uncoordinated amino and carboxylate oxygen atoms of the adjacent layers further stabilize the 3-D framework. Different from AIP in 1, the amino of AIP in 2 and 3 participates in coordination, μ3-bridged AIP connects Co(II) to a 1-D double chain and 2-D layer, respectively, and the subsequent bridge by BIMB and BMIB results in the formation of a 2-D layer and 2-D pillared-bilayer network, respectively. Notably, the coordinated water in complex 2 may be reversibly removed with a concomitant color change and maintenance of the original structural framework. The amino of AIP in 4 and 5 is not involved in coordination, but AIP and BIMB, which has an anti-conformation, in 4 link Mn(II) to a 2-D layer consisting of dinuclear Mn(II)-carboxylate units, while AIP and BMIB, which has an gauche conformation, in 5 links Mn(II) ions to a 1-D chain. Complex 6 is a 3-D pillared-layer structure. It should be mentioned that extensive hydrogen bonds are formed in complexes 1–6. The magnetic study of complex 4 shows that there is a dominant antiferromagnetic coupling above 40 K, while a weak ferromagnetic order is caused by spin-canting at lower temperatures.

In this study, a series of novel D–π–A porphyrin sensitizers with different alkyl chains were designed and synthesized for dye-sensitized solar cells. The effects of different alkyl chains (methyl, methoxyl and hexyloxy groups) on the photophysical, electrochemical and photovoltaic performance were investigated systematically. The results indicate that the molar extinction coefficients of three dyes normally increase as the alkyl chain length increases. Furthermore, it is also found that the incident photo-to-current conversion efficiencies (IPCEs), short circuit current (Jsc) and open circuit voltage (Voc) of the dye-sensitized solar cells (DSSCs) based on WH-C1, YD20 and WH-C2 increase with the elongation of alkyl chains in the order of WH-C1 < YD20 < WH-C2. Accordingly, under standard global air mass 1.5 solar conditions, the optimized WH-C2-sensitized cell could produce a high conversion efficiency (η) of 7.77%, with a Jsc of 13.10 mA cm−2, a Voc of 831.10 mV, and a fill factor (FF) of 0.70.

Here, four D–π–A porphyrin dye molecules with carboxylic acid at the para-position or meta-position of the benzene ring (coded as WH-C4, WH-C1, WH-C6 and WH-C7, respectively) were designed and synthesized for monolithic dye-sensitized solar cells with mesoscopic carbon counter electrodes. Significant optical and electrochemical differences were found for WH-C6 and WH-C7 with carboxylic acid at the meta-position of the benzene ring in comparison with WH-C4 and WH-C1 with carboxylic acid at the para-position of the benzene ring. The influence of anchoring group positions on the photovoltaic performance of corresponding devices was systematically investigated. The devices sensitized by WH-C6 and WH-C7 show inferior open circuit voltage (Voc) and short circuit photocurrent (Jsc) compared with those sensitized by WH-C4 and WH-C1. The above performance differences were confirmed and explained by electrochemical impedance spectroscopy (EIS), UV-visible absorption spectra and dye loading measurement, respectively.