1. Antimicrobial consumption and antimicrobial resistance: a snapshot of an Italian neuromuscular rehabilitation center.
- Author
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Barberi G, De Cola MC, Dell'Utri C, Melardi S, Alagna B, Bramanti P, and Cascio A
- Subjects
- Catheters, Drug Utilization, Intubation, Gastrointestinal, Italy, Risk Factors, Anti-Bacterial Agents administration & dosage, Bacteria drug effects, Drug Resistance, Bacterial, Neuromuscular Diseases rehabilitation, Rehabilitation Centers
- Abstract
The paper presents a snapshot of the incidence of antimicrobial-resistant microorganisms and antimicrobial consumption in an Italian rehabilitation center over a two-year period (2014-2015). Data on microorganism identification and antimicrobial susceptibility testing were obtained from the diagnostic laboratory of the hospital. A set of indicators was assessed, including the incidence density of resistant isolates per 1000 patient-days (IDRI). Data on antimicrobial consumption, semi-annually, obtained from the hospital pharmacy, were expressed as Defined Daily Dose (DDD) per 1000 patient-days. The most frequently isolated microorganism was Klebsiella pneumoniae (19.3%), and a significant increase in piperacillin/tazobactam- resistant K. pneumoniae (p=0.04) was observed. Among all antimicrobials used, carbapenems were the most prescribed antibiotic class (31%).
- Published
- 2017