1. The possible deleterious effects of the intramyometrial injection of hypertonic urea.
- Author
-
Parmley TH, Burnett LS, Blake DA, Miyasaki BC, and King TM
- Subjects
- Animals, Female, Haplorhini, Hypertonic Solutions administration & dosage, Injections, Macaca mulatta, Necrosis, Pregnancy, Saline Solution, Hypertonic administration & dosage, Saline Solution, Hypertonic adverse effects, Urea administration & dosage, Abortifacient Agents adverse effects, Abortifacient Agents, Nonsteroidal adverse effects, Hypertonic Solutions adverse effects, Myometrium pathology, Urea adverse effects, Uterus
- Abstract
Hypertonic urea has been shown to be an effective midtrimester abortifacient. Although safer than hypertonic saline when injected intravascularly, it has not been compared to saline in the case of inadvertent intramyometrial injection. This report documents that intramyometrial injection of hypertonic urea will result in the same type of muscle necrosis as that produced by saline.
- Published
- 1976