1. En-Face Optical Coherence Tomography of Acute Syphilitic Posterior Placoid Chorioretinopathy.
- Author
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Zett, Claudio, Lima, Luiz H, Vianello, Silvana, Ferreira, Adriano, de Andrade, Gabriel Costa, Farah, Michel E, Belfort, Rubens, Zett, Claudio MD, Lima, Luiz H MD, Vianello, Silvana MD, Ferreira, Adriano MD, de Andrade, Gabriel Costa MD, Farah, Michel E MD, Belfort, Rubens Jr. MD PhD, and Belfort, Rubens Jr
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SYPHILIS , *OPTICAL coherence tomography , *TREPONEMA pallidum , *ANGIOGRAPHY , *HIV , *BACTERIAL diseases , *DIAGNOSTIC imaging , *EYE infections , *UVEITIS , *VISUAL acuity , *RETROSPECTIVE studies , *ACUTE diseases - Abstract
Purpose: To report a unique case series of acute syphilitic posterior placoid chorioretinopathy (ASPPC) correlating en-face optical coherence tomography (OCT) with standard imaging modalities.Methods: In this retrospective case series, multimodal imaging was performed in three ASPPC patients at the time of disease presentation.Results: Clinical and laboratory findings were consistent with the diagnosis of ASPPC. In all the study patients, multiple hyperreflective dot-like lesions distributed in the macular area and observed with en-face OCT at the level of retinal pigment epithelium (RPE) corresponded to the nodular RPE elevations on cross-sectional OCT and to the hyperautofluorescent spots on fundus autofluorescence. In addition, the cross-sectional OCT scans showed disorganization of the outer retinal bands and punctate choroidal hyperreflectivity.Conclusion: By combining en-face OCT with multimodal imaging analysis, we propose that a primary inflammation at the level of the choroid may be the pathogenic mechanism for the occurrence of outer retinal band abnormalities. [ABSTRACT FROM AUTHOR]- Published
- 2018
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