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Purpose: To analyze the results of scanning slit topography in both eyes of patients with unilateral Fuchs heterochromic iridocyclitis (FHI). Methods: A noninterventional, case-controlled study was conducted with 30 patients with unilateral FHI. Corneal topographic parameters, obtained with the Orbscan II (Bausch & Lomb), were compared between the two eyes and analyzed statistically. The same number of age-matched normals was enrolled as a control group. Results: Thirty patients were enrolled in this study. The mean age was 33.3 years ±± 10.6 (SD). The mean Sim K astigmatism was 1.65 ±± 1.27 diopter in the FHI eyes and 0.88 ±± 0.52 diopter in the normal eyes ( p == .001). Conclusion: Corneal astigmatism is a common finding in patients with FHI and disparity of corneal astigmatism between the two eyes can be considered a sign of the unilateral form of this disease. [ABSTRACT FROM AUTHOR]

Purpose: To report a rare case of bilateral anterior uveitis with hypopyon formation following systemic topiramate use. Materials and Methods: A 40-year-old woman with migraine headache who was under topiramate treatment referred with bilateral ocular pain and visual blurring. Physical examination disclosed shallow anterior chamber and high intraocular pressure in both eyes. Following discontinuation of topiramate a severe bilateral anterior uveitis with posterior synechiae and hypopyon developed. Results: Ocular inflammation resolved with systemic and topical steroid. Because of severe cataract and synechiae formation she underwent phacoemulsification/posterior chamber intraocular lens implantation and visual acuity of both eyes improved to 20/25. Conclusion: Topiramate should be added to the list of drugs that may cause anterior uveitis and hypopyon formation. [ABSTRACT FROM AUTHOR]