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Start Over Search Limiters Full Text Topic delayed-type hypersensitivity Journal oncoimmunology
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1. Early predictive value of multifunctional skin-infiltrating lymphocytes in anticancer immunotherapy.

Author

Wimmers, Florian, Aarntzen, Erik HJG, Schreibelt, Gerty, Jacobs, Joannes FM, JA Punt, Cornelis, Figdor, Carl G, and de Vries, I Jolanda M

Subjects
LYMPHOCYTES, ANTINEOPLASTIC agents, IMMUNOTHERAPY, BIOLOGICAL assay, T cells, THERAPEUTICS
Abstract

Bioassays that predict clinical outcome are essential to optimize cellular anticancer immunotherapy. We have recently developed a robust and simple skin test to evaluate the capacity of tumor-specific T cells to migrate, recognize their targets and exert effector functions. This bioassay detects T cells with an elevated antineoplastic potential and hence rapidly identifies patients responding to immunotherapy. [ABSTRACT FROM PUBLISHER]

Published
2014
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