1. A comparative dosimetric study of volumetric-modulated arc therapy vs. fixed field intensity-modulated radiotherapy in postoperative irradiation of stage IB-IIA high-risk cervical cancer
- Author
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Lili Qiao, Jian Cheng, Hui Luo, Jian Xie, Jiandong Zhang, and Ning Liang
- Subjects
Cancer Research ,medicine.medical_specialty ,cervical cancer ,medicine.medical_treatment ,Postoperative irradiation ,Rectum ,volumetric-modulated arc radiotherapy ,030218 nuclear medicine & medical imaging ,03 medical and health sciences ,0302 clinical medicine ,medicine ,Dosimetry ,Stage (cooking) ,Cervical cancer ,business.industry ,dosimetry characteristics ,Cancer ,Articles ,intensity-modulated radiotherapy ,medicine.disease ,Surgery ,Radiation therapy ,Fixed field ,medicine.anatomical_structure ,Oncology ,030220 oncology & carcinogenesis ,Nuclear medicine ,business ,therapeutics - Abstract
The aim of the present study was to compare the dosimetry features of volumetric-modulated arc therapy (VMAT) and fixed field intensity-modulated radiotherapy (f-IMRT) in postoperative irradiation of stage IB-IIA high-risk cervical cancer. Fifteen patients exhibiting stage IB-IIA high-risk cervical cancer, who had been treated with postoperative adjuvant concurrent radiochemotherapy, were selected. The clinical target volume (CTV) and organs at risk (OARs) were delineated according to contrast computed tomography images. The planning target volume (PTV) was subsequently produced by using 1 cm uniform expansion of the CTV. The treatment plans were intended to deliver 50 Gy in 25 fractions. The OARs that were contoured included the bladder, rectum, small bowel and femoral heads. Dose volume histograms were used to evaluate the dose distribution in the PTV and OARs. VMAT and f-IMRT treatment plans resulted in similar dose coverage of the PTV. VMAT was superior to f-IMRT in conformity (P
- Published
- 2015