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There have been many studies regarding urinary incontinence in cystic fibrosis females. However, no data concerning that issue was yet investigated in Poland. An anonymous questionnaire was sent by mail to all Polish cystic fibrosis females 16 years of age and older. 64 patients responded to the questionnaire, 44% reported having urinary incontinence. Median age of onset of incontinence was 14.5 years. There were no differences in age, Body Mass Index (BMI), Forced expiratory volume in 1 second (FEV1), Cystic Fibrosis-Related Diabetes and Percutaneous Endoscopic Gastrostomy between continent and incontinent respondents. Significant correlations between urinary incontinence and number of respiratory exacerbations, sexual activity, and constipation were observed. No relationships between frequency and severity of urinary incontinence and form of chest physiotherapy, BMI and FEV1 were identified. Most respondents declared that urinary incontinence affected their daily life and prevented them from chest physiotherapy. Urinary incontinence should be identified and regarded with high priority in cystic fibrosis; health professionals should be aware that it is their responsibility to actively initiate discussion with patients of that subject in early adolescence.