The article focuses on the life and works of M. Judah Folkman, founder of the vascular biology program at Children's Hospital Boston, Massachusetts, who died on January 14, 2008 due to a heart attack. Folkman was born in 1933 in Cleveland, Ohio, and studied at Harvard Medical School, Boston, Massachusetts. It is stated that his work in cancer research led to breakthroughs in treating age-related macular degeneration (AMD). Comments of Folkman's colleagues regarding him have been given.