1. Raman scattering of Cisplatin near silver nanoparticles
- Author
-
Yuri V. Rostovtsev, Nasrin Mirsaleh-Kohan, Michael Duplanty, Mojtaba Moazzezi, and Marjorie Torres
- Subjects
inorganic chemicals ,Materials science ,Physics::Optics ,Nanoparticle ,Nanoprobe ,macromolecular substances ,02 engineering and technology ,01 natural sciences ,Silver nanoparticle ,symbols.namesake ,Optics ,0103 physical sciences ,Microscopy ,Electrical and Electronic Engineering ,Physical and Theoretical Chemistry ,010306 general physics ,Spectroscopy ,Plasmon ,business.industry ,technology, industry, and agriculture ,021001 nanoscience & nanotechnology ,Atomic and Molecular Physics, and Optics ,Electronic, Optical and Magnetic Materials ,symbols ,0210 nano-technology ,business ,Raman spectroscopy ,Raman scattering - Abstract
The Raman scattering of Cisplatin (the first generation of anticancer drugs) has been studied. In the presence of silver nanoparticles, strong modifications of Raman spectra have been observed. The Raman frequencies have been shifted and the line profiles are broadened. We develop a theoretical model to explain the observed features of the Raman scattering. The model takes into account self-consistently the interaction of molecules with surface plasmonic waves excited in the silver nanoparticles, and it provides a qualitative agreement with the observed Raman spectra. We have demonstrated that the using silver nanoparticles can increase sensitivity of the technique, and potentially it has a broader range of applications to both spectroscopy and microscopy.
- Published
- 2018
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