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Your search keyword '"Wang, Hung-Ming"' showing total 34 results
Start Over Author "Wang, Hung-Ming" Journal oral oncology
34 results on '"Wang, Hung-Ming"'

1. Margin-to-depth ratio as an independent prognostic factor in resected oral cavity squamous cell carcinoma: A nationwide cohort study

Author

Klibngern, Hanpon, Kang, Chung-Jan, Lee, Li-Yu, Ng, Shu-Hang, Lin, Chien-Yu, Fan, Kang-Hsing, Chen, Wen-Cheng, Lin, Jin-Ching, Tsai, Yao-Te, Lee, Shu-Ru, Chien, Chih-Yen, Hua, Chun-Hung, Wang, Cheng-Ping, Chen, Tsung-Ming, Terng, Shyuang-Der, Tsai, Chi-Ying, Wang, Hung-Ming, Hsieh, Chia-Hsun, Yeh, Chih-Hua, Lin, Chih-Hung, Tsao, Chung-Kan, Cheng, Nai-Ming, Fang, Tuan-Jen, Huang, Shiang-Fu, Lee, Li-Ang, Fang, Ku-Hao, Wang, Yu-Chien, Lin, Wan-Ni, Hsin, Li-Jen, Yen, Tzu-Chen, Wen, Yu-Wen, and Liao, Chun-Ta

Published
2024
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2. Should sub-millimeter margins be deemed positive in oral cavity squamous cell carcinoma?

Author

Kang, Chung-Jan, Lee, Li-Yu, Ng, Shu-Hang, Lin, Chien-Yu, Fan, Kang-Hsing, Chen, Wen-Cheng, Lin, Jin-Ching, Tsai, Yao-Te, Lee, Shu-Ru, Chien, Chih-Yen, Hua, Chun-Hung, Ping Wang, Cheng, Chen, Tsung-Ming, Terng, Shyuang-Der, Tsai, Chi-Ying, Wang, Hung-Ming, Hsieh, Chia-Hsun, Yeh, Chih-Hua, Lin, Chih-Hung, Tsao, Chung-Kan, Cheng, Nai-Ming, Fang, Tuan-Jen, Huang, Shiang-Fu, Lee, Li-Ang, Fang, Ku-Hao, Wang, Yu-Chien, Lin, Wan-Ni, Hsin, Li-Jen, Yen, Tzu-Chen, Wen, Yu-Wen, and Liao, Chun-Ta

Published
2024
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4. Indications for elective neck dissection in cT1N0M0 oral cavity cancer according to the AJCC eight edition: A nationwide study

Author

Chien, Chih-Yen, Wang, Cheng Ping, Lee, Li-Yu, Lee, Shu-Ru, Ng, Shu-Hang, Kang, Chung-Jan, Lin, Jin-Ching, Terng, Shyuang-Der, Hua, Chun-Hung, Chen, Tsung-Ming, Chen, Wen-Cheng, Tsai, Yao-Te, Tsai, Chi-Ying, Chu, Ying-Hsia, Lin, Chien-Yu, Fan, Kang-Hsing, Wang, Hung-Ming, Hsieh, Chia-Hsun, Yeh, Chih-Hua, Lin, Chih-Hung, Tsao, Chung-Kan, Cheng, Nai-Ming, Fang, Tuan-Jen, Huang, Shiang-Fu, Lee, Li-Ang, Fang, Ku-Hao, Wang, Yu-Chien, Lin, Wan-Ni, Hsin, Li-Jen, Yen, Tzu-Chen, Wen, Yu-Wen, and Liao, Chun-Ta

Published
2023
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5. Clinical outcomes of patients with pT4a and pT4b oral cavity squamous cell carcinoma who had undergone surgery: Results from a Taiwanese registry-based, nationwide cohort study

Author

Kang, Chung-Jan, Wen, Yu-Wen, Lee, Shu-Ru, Ng, Shu-Hang, Lee, Li-Ang, Lee, Li-Yu, Hsueh, Chuen, Lin, Chien-Yu, Fan, Kang-Hsing, Wang, Hung-Ming, Hsieh, Chia-Hsun, Yeh, Chih-Hua, Tsai, Chi-Ying, Lin, Chih-Hung, Tsao, Chung-Kan, Fang, Tuan-Jen, Huang, Shiang-Fu, Fang, Ku-Hao, Wang, Yu-Chien, Lin, Wan-Ni, Hsin, Li-Jen, Yen, Tzu-Chen, Cheng, Nai-Ming, and Liao, Chun-Ta

Published
2022
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6. Improved prognostic stratification of patients with pN3b oral cavity cancer based on maximum standardized uptake value of metastatic nodes, lymph node ratio, and level of cervical nodal metastases

Author

Cheng, Nai-Ming, Kang, Chung-Jan, Tsai, Chi-Ying, Lee, Li-Yu, Lin, Chien-Yu, Hsueh, Chuen, Fan, Kang-Hsing, Wang, Hung-Ming, Hsieh, Chia-Hsun, Ng, Shu-Hang, Yeh, Chih-Hua, Lin, Chih-Hung, Tsao, Chung-Kan, Fang, Tuan-Jen, Huang, Shiang-Fu, Lee, Li-Ang, Fang, Ku-Hao, Wang, Yu-Chien, Lin, Wan-Ni, Hsin, Li-Jen, Yen, Tzu-Chen, and Liao, Chun-Ta

Published
2021
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8. Prognostic stratification of patients with AJCC 2018 pStage IVB oral cavity cancer: Should pT4b and pN3 disease be reclassified?

Author

Kang, Chung-Jan, Tsai, Chi-Ying, Lee, Li-Yu, Lin, Chien-Yu, Yang, Lan-Yan, Cheng, Nai-Ming, Hsueh, Chuen, Fan, Kang-Hsing, Wang, Hung-Ming, Hsieh, Chia-Hsun, Ng, Shu-Hang, Yeh, Chih-Hua, Lin, Chih-Hung, Tsao, Chung-Kan, Fang, Tuan-Jen, Huang, Shiang-Fu, Lee, Li-Ang, Fang, Ku-Hao, Wang, Yu-Chien, Lin, Wan-Ni, Hsin, Li-Jen, Yen, Tzu-Chen, and Liao, Chun-Ta

Published
2021
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9. Clinical outcomes of Taiwanese patients with resected squamous cell carcinoma of the upper and lower gum

Author

Tsai, Chi-Ying, Lee, Shu Ru, Lee, Li-Yu, Hsueh, Chuen, Lin, Chien-Yu, Fan, Kang-Hsing, Wang, Hung-Ming, Hsieh, Chia-Hsun, Ng, Shu-Hang, Yeh, Chih-Hua, Lin, Chih-Hung, Tsao, Chung-Kan, Fang, Tuan-Jen, Huang, Shiang-Fu, Lee, Li-Ang, Kang, Chung-Jan, Fang, Ku-Hao, Wang, Yu-Chien, Lin, Wan-Ni, Hsin, Li-Jen, Yen, Tzu-Chen, Cheng, Nai-Min, Wen, Yu-Wen, and Liao, Chun-Ta

Published
2021
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14. Comparative clinical outcomes of Taiwanese patients with resected buccal and tongue squamous cell carcinomas

Author

Liao, Chun-Ta, Wen, Yu-Wen, Yang, Lan Yan, Lee, Shu Ru, Ng, Shu-Hang, Liu, Tsang-Wu, Tsai, Sen-Tien, Tsai, Ming-Hsui, Lin, Jin-Ching, Chen, Peir-Rong, Lou, Pei-Jen, Wang, Cheng Ping, Chu, Pen-Yuan, Hwang, Tzer-Zen, Leu, Yi-Shing, Tsai, Kuo-Yang, Terng, Shyuang-Der, Chen, Tsung-Ming, Wang, Cheng-Hsu, Chien, Chih-Yen, Chen, Wen-Cheng, Lee, Li-Yu, Lin, Chien-Yu, Wang, Hung-Ming, Hsieh, Chia-Hsun, Tsao, Chung-Kan, Fang, Tuan-Jen, Huang, Shiang-Fu, Kang, Chung-Jan, Chang, Kai-Ping, and Yen, Tzu-Chen

Published
2017
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31. Pretreatment 18F-FDG PET standardized uptake value of primary tumor and neck lymph nodes as a predictor of distant metastasis for patients with nasopharyngeal carcinoma

Author

Hung, Tsung-Min, Wang, Hung-Ming, Kang, Chung-Jan, Huang, Shiang-Fu, Liao, Chun-Ta, Chan, Sheng-Chieh, Ng, Shu-Hang, Chen, I-How, Lin, Chien-Yu, Fan, Kang-Hsing, and Chang, Joseph Tung-Chieh

Subjects
*CANCER tomography, *LYMPHATIC metastasis, *NASOPHARYNX cancer, *CANCER prognosis, *POSITRON emission tomography, *CANCER patients, *COMPARATIVE studies, *CANCER treatment
Abstract

Summary: Objectives: To evaluate the prognostic value of maximum standardized uptake value (SUVmax) measured in [18F]-fluorodeoxyglucose positron emission tomography (18F-FDG PET) for patients with non-disseminated nasopharyngeal carcinoma (NPC). Materials and methods: From January 2002 to July 2008, 371 NPC patients who underwent 18F-FDG-PET before radical intensity-modulated radiotherapy (IMRT) were recruited. The SUVmax was recorded for the primary tumor (SUVmax-T) and neck lymph nodes (SUVmax-N). Results: The median follow-up was 64months. The optimal cutoff value was 9.3 for SUVmax-T and 7.4 for SUVmax-N. Patients with a lower SUVmax-T or SUVmax-N had a significantly better 5-year distant metastasis-free survival (DMFS), but showed no significant difference in local control or regional control. Patients were divided into four groups by SUVmax, as follows: (a) both lower SUVmax-T and SUVmax-N, (b) higher SUVmax-T only, (c) higher SUVmax-N only, and d) both higher SUVmax-T and SUVmax-N. There were significant differences between these four groups in 5-year DMFS: (a) 95.5%, (b) 90.0%, (c) 83.3%, and (d) 79.9%, respectively (p =0.004). When looking at the stage of disease, the 5-year DMFSs in group a, b, c, d were 96.9%, 94.6%, 97.4%, and 84.3%, respectively in stage I–III patients (p =0.037) and were 91.6%, 82.9%, 68.5%, and 76.7% in stage IVA–B patients (p =0.145). Using multivariate analysis, the SUVmax grouping, gender, and stage were independent factors for DMFS. Conclusion: The SUVmax of the primary tumor and neck lymph nodes were independent prognostic factors for DMFS in NPC patients treated with IMRT. [Copyright &y& Elsevier]

Published
2013
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32. Heterogeneity and irregularity of pretreatment 18F-fluorodeoxyglucose positron emission tomography improved prognostic stratification of p16-negative high-risk squamous cell carcinoma of the oropharynx.

Author

Cheng, Nai-Ming, Fang, Yu-Hua Dean, Tsan, Din-Li, Lee, Li-Yu, Chang, Joseph Tung-Chieh, Wang, Hung-Ming, Ng, Shu-Hang, Liao, Chun-Ta, Yang, Lan-Yan, and Yen, Tzu-Chen

Subjects
*SQUAMOUS cell carcinoma, *POSITRON emission tomography, *CHEMORADIOTHERAPY, *PROGRESSION-free survival, *RECEIVER operating characteristic curves, *PROGNOSIS
Abstract

Objectives: Human papillomavirus-negative oropharyngeal squamous cell carcinoma (OPSCC) has unfavorable survival outcomes. Two outcomes have been identified based on smoking history and tumor stage. We investigate the prognostic role of pre-treatment positron emission tomography (PET) in high-risk OPSCC.Materials and Methods: We enrolled 147 M0 OPSCC patients with p16-negative staining and a history of heavy smoking (>10 pack-years) or T4 disease. All patients completed primary chemoradiotherapy, and 42% maximum standard uptake values (SUVmax) were used as the threshold for primary tumor. Patients were classified into training and validation cohorts with a ratio of 1:1.5 according to the PET date. Heterogeneity and irregularity indices were obtained. PET parameters with significant impact on progression-free survival (PFS) in receiver operating characteristic curves and univariate Cox models were identified and included in recursive partitioning analysis (RPA) for constructing a prognostic model. The RPA-based prognostic model was further tested in the validation cohort using multivariate Cox models.Results: Fifty-eight and 89 patients were in the training and validation groups, respectively. Heterogeneity parameter, SUV-entropy (derived from histogram analysis), and irregularity index, and asphericity were significantly associated with PFS. The RPA model revealed that patients with both high SUV-entropy and high asphericity experienced the worst PFS. Results were confirmed in the validation group. The overall concordance index for PFS of the model was 0.75, which was higher than the clinical stages, performance status, SUVmax, and metabolic tumor volume of PET.Conclusions: PET prognostic model provided useful prediction of PFS for patients with high-risk OPSCC. [ABSTRACT FROM AUTHOR]

Published
2018
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33. The role of 18F-FDG PET/CT metabolic tumour volume in predicting survival in patients with metastatic nasopharyngeal carcinoma

Author

Chan, Sheng-Chieh, Hsu, Cheng-Lung, Yen, Tzu-Chen, Ng, Shu-Hang, Liao, Chun-Ta, and Wang, Hung-Ming

Subjects
*CANCER tomography, *POSITRON emission tomography, *NASOPHARYNX cancer, *HEALTH outcome assessment, *TUMOR markers, *CANCER patients, *METASTASIS, *EPSTEIN-Barr virus, *DIAGNOSIS
Abstract

Summary: Objectives: To investigate the role of PET-derived imaging markers in predicting metastatic nasopharyngeal carcinoma (NPC) outcomes. Materials and methods: A total of 56 patients with metastatic NPC were enrolled. Before treatment, all of the participants underwent 18F-FDG PET/CT. The following 18F-FDG PET parameters were assessed: standardised uptake value, metabolic tumour volume (MTV), and total lesion glycolysis. Multivariate Cox proportional hazards models were used to identify the independent predictors of survival. Results: The multivariate analysis showed that performance status>1 (P =0.007), Epstein–Barr virus (EBV) DNA titre>5000copies/mL (P =0.001), and MTV>110mL (P =0.013) were independent risk factors for progression-free survival (PFS). Male sex (P =0.004), performance status>1 (P <0.0001), EBV DNA level>5000copies/mL (P <0.0001), and MTV>110mL (P =0.003) independently predicted overall survival (OS). The 2-year PFS and OS rates of the patients with MTV⩽110mL were 23.2% and 43%, respectively, compared with 0% and 9.1%, respectively, for those with MTV>110mL. Combining the MTV with the EBV DNA titre allowed further survival stratification by dividing the patients into three groups with distinct PFS (2-year rates=30.8%, 7.1%, and 0%, P <0.0001) and OS (2-year rates=68.4%, 40%, and 0%, P <0.0001) rates. Conclusion: The MTV appears to be an independent risk factor in metastatic NPC patients. This factor is complementary to the EBV DNA titre for predicting survival in metastatic NPC. [ABSTRACT FROM AUTHOR]

Published
2013
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34. Pretreatment 18F-FDG PET/CT texture parameters provide complementary information to Epstein-Barr virus DNA titers in patients with metastatic nasopharyngeal carcinoma.

Author

Lin, Huan-Chun, Chan, Sheng-Chieh, Cheng, Nai-Ming, Liao, Chun-Ta, Hsu, Cheng-Lung, Wang, Hung-Ming, Lin, Chien-Yu, Chang, Joseph Tung-Chieh, Ng, Shu-Hang, Yang, Lan-Yan, and Yen, Tzu-Chen

Subjects
*EPSTEIN-Barr virus, *DNA viruses, *TITERS, *RECEIVER operating characteristic curves, *PROPORTIONAL hazards models, *DNA metabolism, *RESEARCH, *RESEARCH methodology, *RETROSPECTIVE studies, *METASTASIS, *EVALUATION research, *MEDICAL cooperation, *COMPARATIVE studies, *RADIOPHARMACEUTICALS, *DEOXY sugars, *LONGITUDINAL method, NASOPHARYNX tumors
Abstract

Purpose: The aim of the present study was to evaluate whether texture features extracted from 18F-FDG PET/CT images may provide additional prognostic information in patients with metastatic nasopharyngeal carcinoma (NPC).Materials and Method: We retrospectively examined 52 patients with metastatic NPC who underwent assessment of EBV DNA titers and pretreatment 18F-FDG PET/CT imaging. All participants were followed up for at least two years. The following 18F-FDG PET parameters were analyzed: standardized uptake value (SUV), metabolic tumor volume (MTV), total lesion glycolysis (TLG), and texture parameters. Independent predictors of outcomes were identified using receiver operating characteristic curve analysis and multivariate Cox proportional hazards models.Results: On multivariate analysis, EBV DNA titers > 3500 copies/mL and TLG of metastatic lesions > 138 mL were identified as independent predictors of overall survival (OS) (P = 0.036 and P = 0.047, respectively). Patients were divided into two subgroups based on their EBV DNA titers (high versus low). In the high EBV DNA titer group, a lower homogeneity of distant metastatic lesions and higher TLG values of distant metastatic lesions were independent risk factors for OS (P = 0.033 and P < 0.001, respectively). In the low EBV DNA titer group, a reduced uniformity of distant metastatic lesions and a higher SUVmax of distant metastatic lesions were unfavorable risk factors for OS (P = 0.004 and P = 0.005, respectively). Based on these results, we devised two prognostic scoring systems for the prediction of 2-year OS in each EBV DNA titer group.Conclusion: Some of the PET-derived texture parameters are independent predictors of outcomes in patients with metastatic NPC and provide complementary information to EBV DNA titers. [ABSTRACT FROM AUTHOR]

Published
2020
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