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1. Concise synthesis of tricyclic isoindolinones via one-pot cascade multicomponent sequences.

Author

Medimagh R, Marque S, Prim D, Marrot J, and Chatti S

Abstract

A series of enantiopure tricyclic isoindolinones has been successfully synthesized through a one-pot selective cascade process from furan derivatives. The synthesis is straightforward and gave good overall yields taking into account the concomitant formation of five C-C, C-O, and C-N bonds. The strategy was extended to the preparation of a thiazolidine analogue.

Published
2009
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