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Your search keyword '"Zhou, Li Li"' showing total 7 results
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7 results on '"Zhou, Li Li"'

6. Cochlearols A and B, polycyclic meroterpenoids from the fungus Ganoderma cochlear that have renoprotective activities.

Author

Dou M, Di L, Zhou LL, Yan YM, Wang XL, Zhou FJ, Yang ZL, Li RT, Hou FF, and Cheng YX

Subjects
Animals, China, Crystallography, X-Ray, Molecular Conformation, Molecular Structure, Rats, Stereoisomerism, Terpenes chemistry, Transforming Growth Factor beta1 drug effects, Ganoderma chemistry, Kidney drug effects, Terpenes isolation & purification, Terpenes pharmacology
Abstract

(+)- and (-)-cochlearols A (1) and B (2), two meroterpenoids with novel polycyclic skeletons, were isolated from the fruiting bodies of the fungus Ganoderma cochlear. Their structures and stereochemistry were determined by using spectroscopic, computational and single-crystal X-ray diffraction methods. Cochlearol A is a new normeroterpenoid containing a naturally unusual dioxaspiro[4.5]decane motif. Biological studies showed that (-)-2 is a strong inhibitor of p-Smads, exhibiting renoprotective activities in TGF-β1 induced rat renal proximal tubular cells.

Published
2014
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7. A novel colorimetric and fluorescent anion chemosensor based on the flavone quasi-crown ether-metal complex.

Author

Zhou LL, Sun H, Li HP, Wang H, Zhang XH, Wu SK, and Lee ST

Abstract

The metal-ligand complex 1 ([Mg (L)] (2+)) (or 2 ([Ca (L)]( 2+))) was demonstrated to selectively bind HSO(4)(-) (or H(2)PO(4)(-)) over other anions by using UV-vis absorption and fluorescence spectroscopy. The studied complex exhibits the remarkable color change and fluorescence quenching upon introducing HSO(4)(-) (or H(2)PO(4)(-)) anion in acetonitrile. Both the mechanism and structure of the secondary complex of complex 1 with anion were proposed on the basis of theoretical computation.

Published
2004
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