14 results on '"Brown, Derek"'
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2. Development of a Commercial Manufacturing Process for Sotorasib, a First-in-Class KRASG12C Inhibitor
3. Axial Chirality in the Sotorasib Drug Substance, Part 2: Leveraging a High-Temperature Thermal Racemization to Recycle the Classical Resolution Waste Stream
4. Development of a Commercial Manufacturing Process for Sotorasib, a First-in-Class KRASG12C Inhibitor.
5. Thermal Hazards of Using Propargyl Alcohol with Strong Bases
6. Hazard Evaluation and Safety Considerations for Scale-Up of a Fuming Nitric Acid Mediated Nitration of Aryl Boronic Acids
7. Process Safety in the Pharmaceutical Industry—Part I: Thermal and Reaction Hazard Evaluation Processes and Techniques
8. A Virtual Plant for Integrated Continuous Manufacturing of a Carfilzomib Drug Substance Intermediate, Part 3: Manganese-Catalyzed Asymmetric Epoxidation, Crystallization, and Filtration
9. Continuous Process Improvement in the Manufacture of Carfilzomib, Part 2: An Improved Process for Synthesis of the Epoxyketone Warhead
10. Hazard Evaluation and Safety Considerations for Scale-Up of a Fuming Nitric Acid Mediated Nitration of Aryl Boronic Acids.
11. Process Safety in the Pharmaceutical IndustryPart I: Thermal and Reaction Hazard Evaluation Processes and Techniques.
12. Safety Notables: Information from the Literature
13. Pilot-Plant Preparation of an αvβ3 Integrin Antagonist. Part 3. Process Research and Development of a Diisopropylcarbodiimide and Catalytic 1-Hydroxybenzotriazole Peptide Coupling
14. Pilot-Plant Preparation of an αvβ3Integrin Antagonist. Part 3. Process Research and Development of a Diisopropylcarbodiimide and Catalytic 1-Hydroxybenzotriazole Peptide Coupling†.
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