1. Syntheses of Nonracemic Ortho-Mercurated and Ortho-Ruthenated Complexes of 2-[Tricarbonyl(η6-phenyl)chromium]pyridine
- Author
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Manon Duquenne, Jérôme Vachon and, Jean-Pierre Djukic, Nathalie Kyritsakas-Gruber, and André De Cian, Michel Pfeffer, Jérôme Lacour, and Alexsandro Berger
- Subjects
Chemistry ,Stereochemistry ,Organic Chemistry ,chemistry.chemical_element ,Medicinal chemistry ,Ruthenium ,Inorganic Chemistry ,Transmetalation ,Chromium ,chemistry.chemical_compound ,ddc:540 ,Pyridine ,Proton NMR ,Physical and Theoretical Chemistry ,Enantiomer - Abstract
The reaction of racemic orthomercurated (η6-arene)tricarbonylchromium complexes with bis[(?6-cymene)ruthenium(II)dichloride] affords the corresponding dinuclear (Cr,Ru) products with moderate yields, which have been satisfactorily characterized by X-ray diffraction analysis. The synthesis of nonracemic orthomercurated (η6-arene)tricarbonylchromium complexes has been attempted starting from enantio-enriched homo- and heteroleptic Pd(II) bischelated complexes. Both enantiomers of ortho-mercurated 2-[tricarbonyl(?6-phenyl)chromium]pyridine have been synthesized by reaction of a heteroleptic Pd(II) bischelated with HgCl2. The two mercury(II) complexes were also submitted to a transmetalation reaction with bis[(?6-cymene)ruthenium(II)dichloride] and yielded the corresponding nonracemic (Cr, Ru) products, with enantiomeric excesses ranging from 82 to 89% as suggested by 1H NMR analyses in the presence of BINPHAT anion.
- Published
- 2004