Search

Purpose of Review: Spinal cord stimulation (SCS) is a minimally invasive and reversible therapy for the treatment of severe neuropathic pain. There are several biologic complications that can arise during the implantation of SCS systems. This review aims to consolidate recent research on complications associated with SCS, specifically focusing on biologic complications., Recent Findings: Biologic complications are less frequently encountered compared to device-related complications but may have more severe consequences. Biologic complications covered in this review include infection, seromas, hematomas, dural puncture, nerve/spinal cord injury, and therapy habituation., Conclusion: The application of SCS remains a viable and effective choice for managing neuropathic pain conditions. It is crucial for physicians to carefully consider potential complications before proceeding with SCS trials and implantation. Familiarity with biologic complications is critical for patient safety and to optimize patient outcomes.