1. The Minimally Clinically Important Difference and Substantial Clinical Benefit in Anterior Cruciate Ligament Reconstruction: A Time-to-Achievement Analysis
- Author
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Adam B. Yanke, Charles A. Bush-Joseph, Brian Forsythe, Yining Lu, Kelechi R. Okoroha, Alexander Beletsky, Brian J. Cole, Edmund Naami, Bernard R. Bach, Evan M. Polce, Jorge Chahla, and Nikhil N. Verma
- Subjects
Adult ,medicine.medical_specialty ,Anterior cruciate ligament reconstruction ,Knee Joint ,medicine.medical_treatment ,Osteoarthritis ,Quality of life ,medicine ,Humans ,Orthopedics and Sports Medicine ,Patient Reported Outcome Measures ,Prospective Studies ,Prospective cohort study ,Anterior Cruciate Ligament Reconstruction ,business.industry ,Minimal clinically important difference ,Anterior Cruciate Ligament Injuries ,Area under the curve ,medicine.disease ,humanities ,Orthopedic surgery ,Physical therapy ,Quality of Life ,Surgery ,business ,Body mass index - Abstract
This study examined the time-dependent course of the minimally clinically important difference (MCID) and the substantial clinical benefit (SCB) achievement for International Knee Documentation Committee (IKDC) and Knee Injury and Osteoarthritis Outcome Score (KOOS) subscales following anterior cruciate ligament reconstruction (ACLR). A prospective institutional registry was queried for patients receiving ACLR. The patient-reported outcome measures (PROMs) of interest included the IKDC score and KOOS sub-scales. One hundred forty-three patients (mean±SD age, 30.86±12.78 years; mean±SD body mass index, 25.51±4.64 kg/m 2 ) were included in the analysis. Threshold values for the MCID/SCB were 18.9 of 29.6 on IKDC score, 15.7 of 25.3 on KOOS Symptom, 11.9 of 15.5 on KOOS Pain, 13.3 of 20.0 on KOOS ADL, 25.9 of 35.8 on KOOS Quality of Life (QoL), and 27.0 of 43.0 on KOOS Sport (area under the curve, 0.74–0.91). Overall, MCID achievement rates increased from 28.0% to 42.7% at 6 months to 41.9% to 70.8% at 12 months. Achievement rates of SCB increased from 16.1% to 30.4% at 6 months to 29.3% to 51.8% at 12 months. Statistically significant increases in MCID achievement (chi-square=47.95–79.36, all P P P Orthopedics . 2021;44(5):299–305.]
- Published
- 2021