249 results on '"Meulenbelt, I."'
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2. ANP32A represses Wnt signaling across tissues thereby protecting against osteoarthritis and heart disease
3. How does hip osteoarthritis differ from knee osteoarthritis?
4. Characterization of dynamic changes in Matrix Gla Protein (MGP) gene expression as function of genetic risk alleles, osteoarthritis relevant stimuli, and the vitamin K inhibitor warfarin
5. Neo-cartilage engineered from primary chondrocytes is epigenetically similar to autologous cartilage, in contrast to using mesenchymal stem cells
6. Radiographic progression of knee osteoarthritis is associated with MRI abnormalities in both the patellofemoral and tibiofemoral joint
7. Hyper-Physiologic Mechanical Loading Conditions Cause A Shift In The Epigenetic Landscape In Neo-Cartilage Organoids
8. Identification Of Circulating Micro Rnas To Predict Osteoarthritis Molecular Endotypes By Whole Transcriptomic Data Integration And Matching Druggable Targets
9. Modelling Senescence In Osteoarthritis: Combining Irradiation And Mechanical Loading In Human Osteochondral Explants
10. High-Impact Fn1 Mutation Abrogates Response Of Chondrocytes To Hyper-Physiological Loading
11. Large scale meta-analysis of urinary C-terminal telopeptide, serum cartilage oligomeric protein and matrix metalloprotease degraded type II collagen and their role in prevalence, incidence and progression of osteoarthritis
12. Association study of candidate genes for the progression of hand osteoarthritis
13. Osteoarthritis year 2011 in review: genetics
14. Summary of the OA biomarkers workshop 2010 – genetics and genomics: new targets in OA
15. Recommendations for standardization and phenotype definitions in genetic studies of osteoarthritis: the TREAT-OA consortium
16. Large-scale meta-analysis of interleukin-1 beta and interleukin-1 receptor antagonist polymorphisms on risk of radiographic hip and knee osteoarthritis and severity of knee osteoarthritis
17. Validity of joint space width measurements in hand osteoarthritis
18. FUNCTIONAL GENOMICS HIGHLIGHTS ROLE FOR OSTEOARTHRITIS SUSCEPTIBILITY GENE WWP2 IN CARTILAGE MATRIX DEPOSITION
19. RNA SEQUENCING REVEALS NOVEL MARKERS AND PATHWAYS OF T3-INDUCED CARTILAGE HYPERTROPHY
20. BLOOD MICRO-RNAS DELINEATING SENESCENCE PHENOTYPES IN OSTEOARTHRITIS
21. A MOLECULAR MAP OF LONG NON-CODING RNA EXPRESSION, ISOFORM SWITCHING AND ALTERNATIVE SPLICING IN OSTEOARTHRITIS
22. TOWARDS APPLICATION OF CELL THERAPY USING HIPSC-DERIVED MSCS AS A STABLE ‘OFF-THE-SHELF’ CELL SOURCE.
23. IDENTIFICATION AND FUNCTIONAL CHARACTERIZATION IMBALANCED OSTEOARTHRITIS ASSOCIATED FIBRONECTIN SPLICE VARIANTS
24. OSTEOARTHRITIS-RISK MUTATION IN PERICELLULAR MATRIX COL6A3 FIBRILS ALTERS BIOLOGIC RESPONSE OF CHONDROCYTES TO HYPER-PHYSIOLOGIC MECHANICAL LOADING CONDITIONS
25. AN EPIGENOME-WIDE VIEW OF OSTEOARTHRITIS IN PRIMARY TISSUES
26. OPPOSITE EFFECTS OF HYPER-PHYSIOLOGICAL MECHANICAL STRESS AND INFLAMMATION ON WNT SIGNALING IN HUMAN CHONDROCYTE NEO-CARTILAGE PELLETS
27. Interleukin-1 region meta-analysis with osteoarthritis phenotypes
28. The role of plasma cytokine levels, CRP and Selenoprotein S gene variation in OA
29. Association of a nsSNP in ADAMTS14 to some osteoarthritis phenotypes
30. Clusters of biochemical markers are associated with radiographic subtypes of osteoarthritis (OA) in subject with familial OA at multiple sites. The GARP study
31. High impact mutation FN1 affects cartilage integrity via aberrant binding to collagen type II
32. An epigenome-wide view of osteoarthritis in target tissues
33. Targeted exploration of an RNA sequencing dataset of preserved and lesioned oa cartilage-establishing a human oa disease model of chondrocyte hypertrophy
34. Mechanical stress induces ADAMTS5 mediated cartilage damage in human neo-cartilage and activates non-canonical Wnt signaling and transcription factor FOS
35. A disease-risk mutation in COL6A3 alters the biologic response of chondrocytes to hyper-physiologic mechanical loading
36. Allelic expression imbalance refined genome-wide association signals in osteoarthritis
37. Development of a human osteochondral construct on a microfluidic chip – to advance functional studies of osteoarthritis risk genes
38. Unravelling the role of osteoprotegerin in osteoarthritis by applying a human isogenic induced pluripotent stem cell model
39. Identifying differential gene expression induced by mechanical stress in cartilage of human explants using RNA-sequencing
40. Large-scale transcriptomic analysis reveals new markers of osteoarthritis progression
41. Large-scale genome-wide meta-analyses provide insights for the development of new disease modifying targets for osteoarthritis
42. Vitamin K antagonist usage is associated with increased incidence and progression of osteoarthritis
43. Characterization of the pathophysiological processes of osteoarthritis using RNA sequencing data of subchondral bone
44. WISP1 expression is responsive to mechanical stress in human primary articular chondrocyte pellets
45. ANP32A is a hub molecule regulating a protective network against osteoarthritis
46. Network-based approach identified distinct pathways between lesioned and preserved articular cartilage transcriptome
47. Long non-coding RNA expression profiling by RNA-sequencing in osteoarthritis cartilage
48. Unravelling the role of WWP2 in the development and progression of osteoarthritis
49. A comparison of chondrogenesis oriented differentiating protocols for induced pluripotent stem cells
50. Unraveling the role of WWP2 in osteoarthritis pathophysiology
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