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The aim of this study is to determine the association of imaging spectrum of hepatocellular carcinoma with post-transplant pattern of metastatic disease.METHOD AND MATERIAL: A seven-year retrospective study (20142020) of live donor liver transplant (LDLT) patients at Shifa International Hospital (SIH) involved comparing pre-transplant CT scans to post-transplant dynamic CT images using a picture archiving and communication system (PACS). Disease recurrence in potential sites, including the hepatic graft, abdomino-pelvic viscera, lungs, bones, and more, was documented. Data was analyzed using frequency statistics, histograms, and tables. RESULTS: Out of 221 transplants, 36 individuals (4F, 32M) experienced recurrences; 27.8% had prior Transarterial chemo-embolization (TACE). Segment VII had the most HCCs (14 patients, 38.9%); Segments V and VI had 6 patients each (16.7%) with average sizes of 4.372 - 1.912 cm. Most patients (69.4%) showed capsular involvement on pre-transplant CT, followed by diaphragmatic involvement in 8, segmental portal venous (PV) tumor in 6, and APS in 3 individuals (22%, 16.7%, 8.3% respectively). Post-transplant CT showed recurrence in the lungs (44.4%), bones (41.6%), hepatic graft (30.5%), lymph nodes (22.2%), adrenals (8.3%), and other sites. Pre-transplant factors had varying associations with recurrence, but none were statistically significant (P-values > 0.05). CONCLUSION: Our study does not show significant association between presence of diaphragmatic involvement, hepatic capsular invasion, thrombosed segmental branches, and arterioportal shunting (APS) and the site of tumor recurrence. However, presence of significant capsular and diaphragmatic bulge particularly in segment VII and VIII HCCs, robust scrutiny should be carried out for evaluation of these areas both intra-operatively by surgeon and in post-transplant follow-up CT reporting by radiologist. Furthermore, in post-transplant CTs, comparison and correlation with pre-transplant CT findings should be carried out. The study also highlights the key role of radiologist in highlighting these features of HCCs for assistance in ensuring safe surgical practices. [ABSTRACT FROM AUTHOR]

OBJECTIVE: The objective of this article is to present imaging findings in tuberous sclerosis complex (TSC), which will eventually help in imaging based diagnosis. STUDY DESIGN: Retrospective study PLACE AND DURATION OF STUDY: Radiology Department, Shifa International Hospital, from 2010 to 2021. METHODOLOGY: Total of 20 patients were selected from the radiology database retrospectively from 2010 to 2021. These patients were diagnosed with Tuberous Sclerosis by radiology department and their scans were performed and reviewed at CT and MRI machines of Shifa International Hospital. CT scan was performed on Toshiba 640 slices, Siemens 128 slices and Siemens 16 slices, and MRI was performed on Siemens 3 tesla, Toshiba-titan 1.5 tesla and Hitachi 0.4 tesla. The literature review was also done to identify different organ system involvement of this disease. RESULT: Different organ system involvement by this disease and imaging features of them are reported. CONCLUSION: TSC has wide range of radiological imaging findings. Recognition of various organ manifestations on imaging is necessary for making the accurate diagnosis and is helpful in the treatment plan. [ABSTRACT FROM AUTHOR]