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Studies dealing with the reconstruction of Holocene climate change of tropical areas are scarce. Of these, multi-proxy investigations using peatlands are still absent. In this paper, we present the Holocene record of environmental changes in central–eastern Brazil reconstructed from a core sampled in Pau de Fruta mire (Serra do Espinhaço Meridional, Brazil). We combined palynological and geochemical analyses, supported by core stratigraphy, 14 C dating and multivariate statistics. The location of the mire is ideal because it is in an area which is directly associated with the South Atlantic Convergence Zone (SACZ). Six main phases of change suggested by vegetation and local and regional landscape dynamics were described. In phase I (~ 10,000–7360 cal. yr BP) the climate was very wet and cold and was accompanied by soil instability in the mire catchment (severe local erosion) and the 8.2 ka event was easily recognizable by a large increase in the deposition of regional dust. Phase II (~ 7360–4200 cal. yr BP) was characterized by wet and warm conditions, catchment soil stability and enhanced deposition of regional dust. In phase III (~ 4200–2200 cal. yr BP), climate was dry and warm and soil erosion in the catchment increased again. In phase IV (~ 2200–1160 cal. yr BP) dry and punctuated cooling was reconstructed, together with enhanced deposition of regional dust. Phase V (~ 1160–400 cal. yr BP) reflects sub-humid climatic conditions (like the current climate), the lowest inputs of local and regional dust and the largest accumulation of peat in the mire. While in phase VI (< ~ 400 cal. yr BP) sub-humid conditions continued but both local and regional erosion significantly increased. Our results demonstrate that the tropical peatlands of Serra do Espinhaço Meridional contain relevant records of Holocene climate changes, and that a multi-proxy approach offers good opportunities for a detailed reconstruction of palaeoenvironments. [ABSTRACT FROM AUTHOR]