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Universities are sources of innovation: they may develop discoveries into marketable innovation while promoting policies that could potentially create a receptive environment for entrepreneurship. Technology transfer may occur to either the public or the private sector. In this way, universities must be involved in activities focused on transferring expertise and technology to user communities, industry, and businesses. A technology transfer office may be understood as a high performance team that guides research to business reality using different strategies. In order to suggest ways to improve communications and co-operation with industry and business community, this paper develops a reference model in which essential steps are presented to drive technology transfer offices to continuous improvement while focusing on strategic ICT planning. The model also considers the importance of training as a preparation for change as well as the creation of a knowledge base composed of case studies describing the transitions considered in each cycle. [ABSTRACT FROM AUTHOR]