1. Auditory event-related potentials in Parkinson's disease: Prominent correlation with attention
- Author
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Hideaki Matsui, Kazuto Nishinaka, Masaya Oda, Tamotsu Kubori, and Fukashi Udaka
- Subjects
Male ,medicine.medical_specialty ,Parkinson's disease ,Auditory event ,Disease ,Neuropsychological Tests ,Audiology ,Correlation ,mental disorders ,medicine ,Humans ,Dementia ,Latency (engineering) ,Aged ,Aged, 80 and over ,Electroencephalography ,Parkinson Disease ,medicine.disease ,Event-Related Potentials, P300 ,nervous system diseases ,Acoustic Stimulation ,Neurology ,Evoked Potentials, Auditory ,Female ,Neurology (clinical) ,Geriatrics and Gerontology ,Psychology - Abstract
Objective : Auditory P300 has been reported to be abnormal in demented patients with Parkinson's disease. However, it is still controversial which factors in Parkinson's disease influence P300 parameters. Methods : Forty patients with Parkinson's disease were included. Patients were divided into two groups: patients with dementia (PDD) and without dementia (PDND). An ‘odd-ball’ paradigm was used for auditory event-related potentials. Results : P300 latency was markedly delayed in PDD patients. Age and DRS1 (attention) were the most important factors influencing P300 latency. Conclusions : Although there have been reports of P300 in the past, its abnormalities reflect the deficit of attention in Parkinson's disease.
- Published
- 2007