1. Corticosteroids in the treatment of severe nocardia pneumonia in chronic granulomatous disease.
- Author
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Freeman AF, Marciano BE, Anderson VL, Uzel G, Costas C, and Holland SM
- Subjects
- Adolescent, Adult, Anti-Bacterial Agents therapeutic use, Anti-Inflammatory Agents therapeutic use, Granulomatous Disease, Chronic drug therapy, Humans, Male, Nocardia Infections diagnosis, Nocardia Infections etiology, Pneumonia, Bacterial diagnosis, Pneumonia, Bacterial etiology, Treatment Outcome, Young Adult, Adrenal Cortex Hormones therapeutic use, Granulomatous Disease, Chronic complications, Nocardia Infections drug therapy, Pneumonia, Bacterial drug therapy
- Abstract
Nocardia is 1 of the 5 main pathogens that infect chronic granulomatous disease patients. Despite aggressive antimicrobial therapy, medical treatment is not always successful and surgical resection of infected tissue has been intermittently required. We present 2 chronic granulomatous disease patients with severe Nocardia pneumonia whose pulmonary status worsened despite appropriate antimicrobials, but then improved clinically and radiographically with the addition of corticosteroids.
- Published
- 2011
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