1. Diagnostic accuracy of urine dipsticks for detecting albuminuria in indigenous and non-indigenous children in a community setting
- Author
-
Pamela Lopez-Vargas, David Lyle, Leigh Haysom, Jonathan C. Craig, L. Paul Roy, Elisabeth M Hodson, and Rita Williams
- Subjects
Male ,medicine.medical_specialty ,Native Hawaiian or Other Pacific Islander ,Population ,urologic and male genital diseases ,Predictive Value of Tests ,Residence Characteristics ,Risk Factors ,Internal medicine ,medicine ,Albuminuria ,Humans ,Mass Screening ,False Positive Reactions ,Child ,education ,False Negative Reactions ,Reagent Strips ,education.field_of_study ,Proteinuria ,business.industry ,Australia ,Reproducibility of Results ,Dipstick ,medicine.disease ,female genital diseases and pregnancy complications ,Endocrinology ,Nephrology ,Predictive value of tests ,Pediatrics, Perinatology and Child Health ,Diagnostic odds ratio ,Female ,medicine.symptom ,business ,Body mass index ,Follow-Up Studies ,Kidney disease - Abstract
Albuminuria predicts cardiovascular and end-stage kidney disease in indigenous populations. Early detection in indigenous children may identify those who could benefit from early treatment. Community-based detection of albuminuria needs to be performed using a reliable, inexpensive, and widely available test, such as a proteinuria dipstick. Dipstick accuracy for detecting albuminuria in a community setting has not been evaluated. We assessed the accuracy of Multistix 10 SG dipsticks to detect baseline albuminuria and predict for persistent albuminuria at a 2-year follow-up in a population-based cohort of Australian Aboriginal and non-Aboriginal elementary-school-aged children. Variability in the accuracy of dipsticks in subgroups of higher risk children was analyzed using the relative diagnostic odds ratio (RDOR). Using Multistix 10 SG dipsticks, index-test-positive cases were defined as ≥0.30 g/L (1+) proteinuria and index-test-negative cases as
- Published
- 2009