Aim: To evaluate whether clamping time could affect peripheral and heart hemodynamics, in a group of healthy term newborns. Subjects and Methods: We evaluated 9 early cord clamping (ECC) (30 seconds) in comparison with 10 late cord clamping neonates (LCC) (4 minutes) at the mean age of 68.7 hrs. The following variables were evaluated: hematocrit (Ht %), hemoglobin (Hb g/dL), total bilirubin (TB mg/dL), heart left diastolic ventricular diameter LDV(D) (cm) by a sonographer (HDI 3000 CV); calf blood flow (mL/100g/min), calf Hb flow (micromoles/100 mL/min), calf O2 delivery (DO2), O2 consumption (VO2) (micromoles/100 mL/min), using near-infrared spectroscopy (NIRS, NIRO 300 oximeter). Perfusion index (PI) were obtained using a Masimo SET radical pulse oximeter with a sensor placed on the foot contralateral. Data are presented as mean (SD). Mann Whitney test was used to compare the two groups values. A p value less than 0.05 was considered significant. Results: Ht 55.5 (4.8) vs 64.5 (5.3) (p 0.004) in ECC and LCC groups respectively, Hb 15.2 (1.2) vs 17.9 (1.4) (p 0.002), TB 8.2 (3.6) vs 7.3 (2.8) (ns), calf Hb flow 2.1 (1.4) vs 1.9 (0.9) (ns), calf BF 0.7 (0.4) vs 0.7 (0.3) (ns), calf DO2 10.1 (1.3) vs 11.2 (1.1) (ns), calf VO2 calculated by arterial occlusion 0.4 (0.1) vs 0.3 (0.1) (ns), LDV(D) 1.5 (0.08) vs 1.7 (0.1) (p 0.01), and foot PI 1.08 (0.3) vs 1.1 (0.3) (ns). Conclusion: Our study shows that LCC group has an increased placental transfusion, that was expressed by higher hematocrit and hemoglobin, in comparison with ECC group; so a bigger left ventricle diameter at the diastole. There was no evidence of changing in both calf Hb flow and blood flow, as well as in oxygen tissue metabolic demand and foot PI. The increased blood volume seems not to increase the jaundice risk.