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Your search keyword '"Özbek, Namık Yaşar"' showing total 5 results
Start Over Author "Özbek, Namık Yaşar" Journal pediatric transplantation
5 results on '"Özbek, Namık Yaşar"'

1. COVID‐19 disease in children and adolescents following allogeneic hematopoietic stem cell transplantation: A report from the Turkish pediatric bone marrow transplantation study group

Author

Bozkurt, Ceyhun, primary, Hazar, Volkan, additional, Malbora, Barış, additional, Küpesiz, Alphan, additional, Aygüneş, Utku, additional, Fışgın, Tunç, additional, Karakükçü, Musa, additional, Kuşkonmaz, Barış, additional, Kılıç, Suar Çakı, additional, Bayırlı, Derya, additional, Arman Bilir, Özlem, additional, Yalçın, Koray, additional, Gözmen, Salih, additional, Uygun, Vedat, additional, Elli, Murat, additional, Sarbay, Hakan, additional, Küpesiz, Funda Tayfun, additional, Şaşmaz, Hatice İlgen, additional, Aksoy, Başak Adaklı, additional, Yılmaz, Ebru, additional, Okur, Fatma Visal, additional, Tekkeşin, Funda, additional, Yenigürbüz, Fatma Demir, additional, Özek, Gülcihan, additional, Atay, Abdullah Avni, additional, Bozkaya, İkbal Ok, additional, Çelen, Suna, additional, Öztürkmen, Seda, additional, Güneş, Adalet Meral, additional, Gürsel, Orhan, additional, Güler, Elif, additional, Özcan, Alper, additional, Çetinkaya, Duygu Uçkan, additional, Aydoğdu, Selime, additional, Özbek, Namık Yaşar, additional, Karasu, Gülsün, additional, Sezgin, Gülay, additional, Doğru, Ömer, additional, Albayrak, Davut, additional, Öztürk, Gülyüz, additional, Aksoylar, Serap, additional, Daloğlu, Hayriye, additional, Odaman Al, Işık, additional, Evim, Melike Sezgin, additional, Akbayram, Sinan, additional, Öncül, Yurday, additional, Zengin, Emine, additional, Albayrak, Canan, additional, Timur, Çetin, additional, Kar, Yeter Düzenli, additional, Çakmaklı, Hasan Fatih, additional, Tüfekçi, Özlem, additional, Töret, Ersin, additional, and Antmen, Bülent, additional

Published
2024
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3. Monitoring of adenoviremia in pediatric patients undergoing hematopoietic stem cell transplantation: Is it alone sufficient to predict adenoviral disease?

Author

Kanık Yüksek, Saliha, Arman Bilir, Özlem, Erat, Tuğba, Gülhan, Belgin, Kanbur, Şerife Mehtap, Bayhan, Gülsüm İclal, Ok Bozkaya, İkbal, Özkaya Parlakay, Aslınur, and Özbek, Namık Yaşar

Subjects
STEM cell transplantation, HEMATOPOIETIC stem cell transplantation, ADENOVIRUS diseases, CHILD patients, BK virus
Abstract

Background: We aimed to evaluate our pediatric HSCT recipients routinely monitored for adenoviremia and to determine the adequacy of this monitoring in predicting adenoviral disease (AD). Methods: A retrospective cohort of patients who underwent allogeneic HSCT between January 2021 and August 2022, and routinely monitored for adenoviremia by real‐time PCR was included in our survey. Demographic and clinical data of the patients were recorded. Incidence rates, risk factors, and mortality rates related to adenoviremia, and AD were analyzed. Results: Among 104 HSCTs performed in 94 patients adenovirus (AdV) was revealed in 27 (26%) episodes and adenoviremia in 18 (17.3%) HSCT episodes. AD without adenoviremia developed in nine episodes (8.6%). Disseminated disease was significantly more frequently detected in episodes with adenoviremia (p =.008). GVHD was independent risk factor for AdV detection (OR: 8.6, 95% CI: 2.03–33.7, p =.001). Viremia developed within a shorter time interval after HSCT in isolated episodes of adenoviremia compared to those with concomitant AD (p =.006). Initial and peak viral loads were significantly higher in adenoviremia with AD (p <.001). Mortality was higher in the AdV‐detected episodes (p <.001) than in the AdV‐undetected episodes. AdV‐related mortality was found to be 22.2%. Adenoviremia increased the risk of mortality (OR: 1.2, 95% CI: 0.22–1.33, p =.01). Conclusions: Adenoviremia monitoring is an important process in the detection of AD. Since some patients may develop AD without accompanying by adenoviremia, monitoring for AdV in blood samples should be supported with other monitoring methods in order to evaluate the probable involvement of different organs or systems. [ABSTRACT FROM AUTHOR]

Published
2024
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