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Your search keyword '"Carolynn DeByle"' showing total 2 results
Start Over Author "Carolynn DeByle" Journal pediatrics
2 results on '"Carolynn DeByle"'

1. The AlaskaHaemophilus influenzaeType b Experience: Lessons in Controlling a Vaccine-Preventable Disease

Author

Jay C. Butler, Alan J. Parkinson, Thomas W. Hennessy, Lisa R. Bulkow, Tammy Cottle, Laura L. Hammitt, Helen Peters, Rosalyn J. Singleton, and Carolynn DeByle

Subjects
Male, Rural Population, medicine.medical_specialty, Haemophilus Infections, Urban Population, Disease, White People, Bacterial Proteins, Conjugate vaccine, Internal medicine, medicine, Humans, Bacterial Capsules, Meningitis, Haemophilus, Haemophilus Vaccines, Disease surveillance, Vaccines, Conjugate, business.industry, Incidence, Incidence (epidemiology), Polysaccharides, Bacterial, Vaccination, Haemophilus influenzae type b, Infant, medicine.disease, Haemophilus influenzae, Carriage, Immunization, Inuit, Child, Preschool, Population Surveillance, Carrier State, Pediatrics, Perinatology and Child Health, Indians, North American, Female, business, Meningitis, Alaska, Bacterial Outer Membrane Proteins
Abstract

OBJECTIVE. Before 1991, Alaska Native children experienced one of the highest rates of invasive Haemophilus influenzae type b disease. H influenzae type b vaccine has led to a near-elimination of invasive H influenzae type b disease in the United States. We describe challenges encountered in controlling H influenzae type b disease in Alaska and update the current status of H influenzae disease and carriage in Alaska as lessons to other populations.PATIENTS AND METHODS. We reviewed data from statewide H influenzae disease surveillance conducted during 1980–2004. Vaccine coverage data were based on audits from tribal facilities and the National Immunization Survey. H influenzae type b colonization data were based on 6 carriage studies.RESULTS. After universal infant vaccination in 1991, H influenzae type b disease among Alaska Native and non-Native children CONCLUSIONS. H influenzae type b vaccination has resulted in a dramatic decrease in invasive H influenzae type b disease in Alaska; however, despite high rates of H influenzae type b vaccine coverage, H influenzae type b disease rates among rural Alaska Native children

Published
2006
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2. Risk factors for hospitalization with lower respiratory tract infections in children in rural Alaska

Author

Lisa R. Bulkow, Rosalyn J. Singleton, Carolynn DeByle, Thomas W. Hennessy, Karen Miernyk, Gregory J. Redding, Lori Chikoyak, and Kimberlee Boyd Hummel

Subjects
Male, Rural Population, medicine.medical_specialty, Cross-sectional study, Population, Pneumonia, Viral, Psychosocial Deprivation, Human metapneumovirus, Risk Factors, Internal medicine, Lower respiratory tract infection, medicine, Humans, Intensive care medicine, education, education.field_of_study, biology, Respiratory tract infections, business.industry, Infant, Odds ratio, Length of Stay, biology.organism_classification, medicine.disease, Hospitalization, Human Parainfluenza Virus, Cross-Sectional Studies, Logistic Models, Socioeconomic Factors, Case-Control Studies, Child, Preschool, Pediatrics, Perinatology and Child Health, Female, business, Viral load, Alaska
Abstract

OBJECTIVE: Lower respiratory tract infections (LRTIs) are a major cause of morbidity for children worldwide and particularly for children from developing and indigenous populations. In this study, we evaluated risk factors for hospitalization with LRTI in a region in southwest Alaska. METHODS: The study was conducted from October 1, 2006, to September 30, 2007, in the Yukon Kuskokwim Delta region of Alaska. Cases were recruited from children RESULTS: One hundred twenty-eight cases were matched to 186 controls. In a multivariable conditional logistic regression model, significantly (P < .05) increased risk of hospitalization was associated with medically high-risk status, having a woodstove in the house, being bottle fed, and vomiting after feeding; living in a house that had 2 or more rooms with sinks was a protective factor. Viral loads in hospitalized cases were significantly higher than those in controls, but a strict cutoff level was not observed. CONCLUSIONS: Several risk factors for LRTI hospitalization were identified in this high risk population. Some factors are amenable to environmental and behavioral interventions.

Published
2012

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