1. Demodex Folliculitis and Recent Dupilumab Administration.
- Author
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Krakowski AC, Senft SC, and Heymann WR
- Subjects
- Adolescent, Animals, Antibodies, Monoclonal, Humanized administration & dosage, Antiparasitic Agents administration & dosage, Child, Dermatitis, Atopic drug therapy, Facial Dermatoses drug therapy, Humans, Ivermectin administration & dosage, Male, Mite Infestations drug therapy, Mites, Antibodies, Monoclonal, Humanized adverse effects, Facial Dermatoses parasitology, Folliculitis parasitology, Immunomodulation, Mite Infestations complications
- Abstract
Two adolescent boys presented with acute acneiform eruptions in the setting of recent dupilumab administration. Subsequent investigation via direct scraping of pustules revealed live Demodex mite colonization of the face. These adolescent patients represent a population not commonly associated with Demodex folliculitis, and we theorize their baseline commensal Demodex mite population may have increased as a consequence of dupilumab-induced, focused immunomodulation. We recommend that pediatricians consider Demodex potentially etiologic in patients presenting with new onset acneiform or rosacea-like dermatoses in patients treated with dupilumab., Competing Interests: POTENTIAL CONFLICT OF INTEREST: The authors have indicated they have no potential conflicts of interest to disclose., (Copyright © 2021 by the American Academy of Pediatrics.)
- Published
- 2021
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