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Start Over Author "Haruna, Nakaseko" Journal pediatrics international : official journal of the japan pediatric society
1 results on '"Haruna, Nakaseko"'

1. Diffuse alveolar hemorrhage secondary to ANCA-associated vasculitis in a patient with Down syndrome

Author

Ikumi, Hori, Haruna, Nakaseko, Michi, Kamei, Takayasu, Nomura, Naomi, Iwata, Yasuhiko, Ito, and Shinji, Saitoh

Subjects
Lung Diseases, Pulmonary Alveoli, Child, Preschool, Azathioprine, Humans, Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis, Female, Hemorrhage, Down Syndrome, Tomography, X-Ray Computed, Glucocorticoids, Immunosuppressive Agents
Abstract

Diffuse alveolar hemorrhage (DAH) is a rare disease characterized by dyspnea, cough, hemoptysis, and new alveolar infiltrates. Among the various underlying disorders, vasculitis is believed to play a significant role in the pathogenesis of DAH. Here we report the first case of a patient with Down syndrome who developed DAH secondary to anti-neutrophil cytoplasmic antibody-associated vasculitis. This case highlights the significance of vasculitis as well as pulmonary hypoplasia and vulnerability associated with Down syndrome in the development of DAH.

Published
2014

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