1. Current and future periodontal tissue engineering
- Author
-
Yuichi Izumi, Minoru Ueda, Akira Aoki, Takanori Iwata, Tatsuya Akizuki, Sayaka Nakamura, Isao Ishikawa, Nawarat Wara-aswapati, Tomonari Suda, Yoichi Yamada, and Hiroaki Kobayashi
- Subjects
Periodontitis ,Periodontal tissue ,Periodontal treatment ,business.industry ,Regeneration (biology) ,medicine.medical_treatment ,Laser treatment ,Dentistry ,Stem-cell therapy ,Bone grafting ,medicine.disease ,Tissue engineering ,medicine ,Periodontics ,business - Abstract
Periodontitis is an inflammatory disease that leads to the loss of tooth-supporting tissues. Conventional periodontal treatment is generally unable to promote regeneration of the damaged periodontal structures. Recently, several studies have investigated the use of tissue engineering to facilitate predictable periodontal regeneration. This article reviews various technologies related to periodontal tissue engineering. These include bone grafting, guided tissue regeneration, enamel matrix protein derivative, growth factors, stem cell therapy, cell sheet engineering and laser treatment. Studies carried out by this group, and available clinical data, together with the authors own clinical experiences, are discussed. In addition, possible new directions that need to be exploited to make periodontal tissue engineering a clinical success are discussed herein.
- Published
- 2011